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AB2596

Anti-Adenovirus type 1 hexon E11 抗体 [1-M-13]

Anti-Adenovirus type 1 hexon E11 antibody [1-M-13]

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(4 Publications)

Mouse Monoclonal Adenovirus type 1 hexon E11 antibody. Suitable for IP, ELISA, WB and reacts with Adenovirus samples. Cited in 4 publications. Immunogen corresponding to Virus preparation containing Adenovirus type I protein.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

1-M-13

アイソタイプ

IgG2a

軽鎖のタイプ

unknown

キャリアフリー

No

交差種

Adenovirus

アプリケーション

IP, WB, ELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

エピトープ

The exact epitope recognised by this antibody has not been mapped.

特異性

This antibody is specific for Adenovirus type 1 hexon E11.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Adenovirus": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
バッファー組成
pH: 7.2 - 7.6 Preservative: 0.01% Sodium azide
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Adenovirus type 1 hexon E11 also called hexon protein is the largest and main structural protein of adenovirus capsid with a mass of approximately 110 kDa. It forms the icosahedral capsid by creating a trimeric complex that covers most of the viral surface. This protein is highly expressed in adenovirus-infected host cells during the late phase of infection. Hexon protein contains loops that present variable regions which are targets for the host immune response.
Biological function summary

The hexon protein contributes critically to the stability and structure of adenovirus particles and assists in viral entry and disassembly inside the host cell. As part of the adenovirus capsid complex it interacts with other viral proteins such as penton base and fiber proteins. This protein also plays a role in immune evasion by binding to cellular molecules that modulate host immune response.

Pathways

The hexon protein is involved in the viral entry pathway influencing the attachment and internalization of the virus into host cells. The internalization often involves interactions with the CAR (Coxsackie and adenovirus receptor) protein. Additionally it participates in the adenovirus replication pathway where multiple viral proteins including the DNA polymerase coordinate for successful viral replication within the host cell.

Adenovirus type 1 hexon E11 is associated with respiratory tract infections and conjunctivitis. These infections can occur particularly in immunocompromised individuals. The hexon protein interacts with host proteins including integrins to mediate infection of epithelial cells therefore contributing to the pathology of these conditions.

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Journal for immunotherapy of cancer 13: PubMed40169285

2025

Targeted release of a bispecific fusion protein SIRPα/Siglec-10 by oncolytic adenovirus reinvigorates tumor-associated macrophages to improve therapeutic outcomes in solid tumors.

Applications

Unspecified application

Species

Unspecified reactive species

Yenan Zhang,Bohao He,Peng Zou,Mengdi Wu,Min Wei,Chuning Xu,Jie Dong,Jiwu Wei

Cardiovascular research 120:644-657 PubMed38309955

2024

ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.

Applications

Unspecified application

Species

Unspecified reactive species

Clara Bredow,Fabien Thery,Eva Katrin Wirth,Sarah Ochs,Meike Kespohl,Gunnar Kleinau,Nicolas Kelm,Niclas Gimber,Jan Schmoranzer,Martin Voss,Karin Klingel,Joachim Spranger,Kostja Renko,Markus Ralser,Michael Mülleder,Arnd Heuser,Klaus-Peter Knobeloch,Patrick Scheerer,Jennifer Kirwan,Ulrike Brüning,Nikolaus Berndt,Francis Impens,Antje Beling

Journal of neuropathology and experimental neurology 81:414-433 PubMed35521963

2022

Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Raymond A Sobel,Megan Albertelli,Julian R Hinojoza,Mary Jane Eaton,Kevin V Grimes,Edward Rubenstein

Cancer gene therapy 22:445-53 PubMed26251031

2015

Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells.

Applications

Unspecified application

Species

Unspecified reactive species

Y Takei,S Okamoto,K Kawamura,Y Jiang,T Morinaga,M Shingyoji,I Sekine,S Kubo,Y Tada,K Tatsumi,H Shimada,K Hiroshima,N Yamaguchi,M Tagawa
View all publications

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