AB36851

Anti-Adenovirus 抗体

Name: Anti-Adenovirus 抗体 (ab36851) | Abcam
Brand: Abcam Limited
SKU: AB36851
Price: 75000 JPY
Availability: InStock

Anti-Adenovirus antibody

Be the first to review this product! Submit a review

(6 Publications)

Goat Polyclonal Adenovirus antibody. Suitable for ELISA, WB, ICC/IF and reacts with Adenovirus samples. Cited in 6 publications. Immunogen corresponding to Virus preparation containing Adenovirus Type 5 protein.

別名を表示する

Adenovirus

Key facts

宿主種

Goat

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Adenovirus

アプリケーション

ELISA, WB, ICC/IF

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Adenovirus": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

style

left-column

style

left-column

出荷温度及び保存条件

製品の状態

Liquid

精製方法

Ion exchange chromatography

精製に関する特記事項

>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.

バッファー組成

Preservative: 0.1% Sodium azide Constituents: PBS

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

style

left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Adenovirus also known by alternate names such as Adenoviren and Ad51 represents a group of medium-sized non-enveloped viruses with a double-stranded DNA genome. The adenovirus is approximately 90-100 nm in size and is notable for its icosahedral capsid structure. It primarily infects epithelial cells in the respiratory and gastrointestinal tracts but it can also affect other tissues. Its presence is recorded in diverse environments often acting as pathogens in humans and other animals.

Biological function summary

Adenoviruses function by hijacking the host cell's machinery to replicate their DNA and produce viral proteins. They do not form part of a larger complex; instead they independently orchestrate the synthesis of viral particles. Their proteins manipulate host cellular processes leading to cell lysis and viral release. Adenoviral proteins such as E1A and E1B play critical roles in their replication cycles and pathogenicity.

Pathways

Adenoviruses interact closely with pathways involved in cell cycle regulation and apoptosis. These viruses exploit cell cycle-associated proteins like p53 and Rb to immortalize host cells and evade apoptosis respectively. By bypassing normal regulatory checkpoints adenoviruses can ensure continuous replication and survival within the host.

Adenoviruses are commonly associated with conditions like acute respiratory diseases and gastroenteritis. They have a significant connection to the immune responses triggered in infected patients often involving proteins such as cytokines and chemokines. In some cases adenovirus-related infections can lead to severe outcomes in individuals with compromised immune systems demonstrating their impact on human health.

style

left-column

style

left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

ターゲットの情報

See full target information Adenovirus

style

left-column

文献 (6)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 5:106 PubMed35115660

2022

Carvedilol targets β-arrestins to rewire innate immunity and improve oncolytic adenoviral therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Joseph I Hoare,Bleona Osmani,Emily A O'Sullivan,Ashley Browne,Nicola Campbell,Stephen Metcalf,Francesco Nicolini,Jayeta Saxena,Sarah A Martin,Michelle Lockley

Cancers 12: PubMed32224979

2020

External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase.

Applications

Unspecified application

Species

Unspecified reactive species

Tzveta D Pokrovska,Egon J Jacobus,Rathi Puliyadi,Remko Prevo,Sally Frost,Arthur Dyer,Richard Baugh,Gonzalo Rodriguez-Berriguete,Kerry Fisher,Giovanna Granata,Katharine Herbert,William K Taverner,Brian R Champion,Geoff S Higgins,Len W Seymour,Janet Lei-Rossmann

Molecular therapy oncolytics 16:289-301 PubMed32195317

2020

NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Elaine Y L Leung,Darren P Ennis,Philippa R Kennedy,Christopher Hansell,Suzanne Dowson,Malcolm Farquharson,Pavlina Spiliopoulou,Jaya Nautiyal,Sophie McNamara,Leo M Carlin,Kerry Fisher,Daniel M Davis,Gerard Graham,Iain A McNeish

Antiviral research 153:78-84 PubMed29501624

2018

Bivalent vaccine platform based on ca influenza virus vaccine elicits protective immunity against human adenoviruses.

Applications

Species

Unspecified reactive species

Hongjing Gu,Yaqian Gao,Shanshan Zhou,Fang Sun,Zhongpeng Zhao,Keyu Wang,Lingna Zhao,Peirui Zhang,Zhaohai Wang,Shaogeng Zhang,Xiliang Wang,Penghui Yang

Cell death & disease 8:3206 PubMed29238045

2017

RIPK3 promotes adenovirus type 5 activity.

Applications

IHC

Species

Unspecified reactive species

Melanie Weigert,Alex Binks,Suzanne Dowson,Elaine Y L Leung,Dimitris Athineos,Xinzi Yu,Margaret Mullin,Josephine B Walton,Clare Orange,Darren Ennis,Karen Blyth,Stephen W G Tait,Iain A McNeish

Molecular cancer research : MCR 14:44-55 PubMed26452665

2015

RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer.

Applications

Species

Unspecified reactive species

Laura A Tookman,Ashley K Browne,Claire M Connell,Gemma Bridge,Carin K Ingemarsdotter,Suzanne Dowson,Atsushi Shibata,Michelle Lockley,Sarah A Martin,Iain A McNeish

View all publications

style

left-column

style

left-column

style

right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Adenovirus 抗体

Anti-Adenovirus antibody

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

精製に関する特記事項

バッファー組成

出荷温度

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (6)

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise