Anti-ADAM9 抗体 (ab186833)
Key features and details
- Rabbit polyclonal to ADAM9
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-ADAM9 antibody
ADAM9 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ADAM9 -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant fragment corresponding to Human ADAM9 aa 475-685 (internal sequence).
Database link: Q13443 -
ポジティブ･コントロール
- Mouse kidney and liver extracts.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab186833の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use at an assay dependent concentration.
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| WB |
1/500 - 1/2000. Predicted molecular weight: 91 kDa.
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| IHC-P |
1/50 - 1/200.
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| 特記事項 |
|---|
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ICC/IF
Use at an assay dependent concentration. |
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WB
1/500 - 1/2000. Predicted molecular weight: 91 kDa. |
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IHC-P
1/50 - 1/200. |
ターゲット情報
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関連性
ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. -
細胞内局在
Isoform 1: Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein. -
参照データベース
- Entrez Gene: 8754 Human
- Entrez Gene: 11502 Mouse
- Omim: 602713 Human
- SwissProt: Q13443 Human
- SwissProt: Q61072 Mouse
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別名
- A disintegrin and metalloproteinase domain 9 antibody
- ADAM 9 antibody
- ADAM metallopeptidase domain 9 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ADAM9 antibody (ab186833)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver cancer tissue labelling ADAM9 with ab186833 at 1/200. Magnification: 400x.
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Immunocytochemistry/ Immunofluorescence - Anti-ADAM9 antibody (ab186833)Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab186833. Blue DAPI for nuclear staining. -
Western blot - Anti-ADAM9 antibody (ab186833)All lanes : Anti-ADAM9 antibody (ab186833) at 1/500 dilution
Lane 1 : Mouse kidney extract
Lane 2 : Mouse liver extract
Predicted band size: 91 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (17)
ab186833 は 17 報の論文で使用されています。
- Pan C et al. Licochalcone A Inhibits Proliferation and Metastasis of Colon Cancer by Regulating miR-1270/ADAM9/Akt/NF-κB axis. Iran J Public Health 52:1962-1972 (2023). PubMed: 38033851
- Xiao Y et al. Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation. Mol Oncol 16:388-404 (2022). PubMed: 33811456
- Li D et al. IL-17A Promotes Epithelial ADAM9 Expression in Cigarette Smoke-Related COPD. Int J Chron Obstruct Pulmon Dis 17:2589-2602 (2022). PubMed: 36267325
- Goel K et al. Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension. Respir Res 23:349 (2022). PubMed: 36522710
- Ma D et al. Long Non-coding RNA RUNDC3A-AS1 Promotes Lung Metastasis of Thyroid Cancer via Targeting the miR-182-5p/ADAM9. Front Cell Dev Biol 9:650004 (2021). PubMed: 34046406