Anti-Activin Receptor Type IIA/ACVR2A 抗体 [MM0058-6J16] (ab78412)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16] (ab78412)](https://www.abcam.co.jp/ps/products/78/ab78412/Images/Activin-Receptor-Type-IIA-Primary-antibodies-ab78412-1.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16] (ab78412)")
Key features and details
- Mouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA/ACVR2A
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2
製品の概要
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製品名
Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16]
Activin Receptor Type IIA/ACVR2A 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA/ACVR2A -
由来種
Mouse -
特異性
Specific for human Activin RIIA. No cross reactivity was found to hActivin RI and RIIB. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse
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免疫原
Recombinant fragment corresponding to Activin Receptor Type IIA/ACVR2A.
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ポジティブ･コントロール
- IHC-P: Human placenta tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
MM0058-6J16 -
アイソタイプ
IgG2 -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab78412の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/50 - 1/100.
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| 特記事項 |
|---|
|
IHC-P
1/50 - 1/100. |
ターゲット情報
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機能
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. -
配列類似性
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 92 Human
- Entrez Gene: 11480 Mouse
- Omim: 102581 Human
- SwissProt: P27037 Human
- SwissProt: P27038 Mouse
- Unigene: 470174 Human
- Unigene: 314338 Mouse
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別名
- Activin A receptor type IIA antibody
- Activin receptor type 2A antibody
- Activin receptor type IIA antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16] (ab78412)
ab78412 at 1/100 dilution staining Activin Receptor Type IIA/ACVR2A in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin embedded sections).
データシートおよび資料
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Datasheet download
参考文献 (1)
ab78412 は 1 報の論文で使用されています。
- Lin TT et al. Follicular localization of growth differentiation factor 8 and its receptors in normal and polycystic ovary syndrome ovaries. Biol Reprod 98:683-694 (2018). PubMed: 29409020
