Anti-ABIN3 抗体 (ab113748)
Key features and details
- Rabbit polyclonal to ABIN3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ABIN3 antibody
ABIN3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ABIN3 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse
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免疫原
Synthetic peptide corresponding to Human ABIN3 (C terminal) conjugated to keyhole limpet haemocyanin.
Database link: Q96KP6 -
ポジティブ･コントロール
- IHC-P: Human adrenal tissue WB: Human spleen tissue lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113748の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
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| IHC-P |
Use a concentration of 5 µg/ml.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
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関連性
ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3. -
細胞内局在
Cytoplasmic and Nuclear (based on other ABIN family members). -
参照データベース
- Entrez Gene: 79931 Human
- Entrez Gene: 414084 Mouse
- Omim: 608019 Human
- SwissProt: Q96KP6 Human
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別名
- A20 binding inhibitor of NF kappa B activation 3 antibody
- ABIN 3 antibody
- ABIN 3 beta antibody
see all
画像
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Western blot - Anti-ABIN3 antibody (ab113748)All lanes : Anti-ABIN3 antibody (ab113748) at 1 µg/ml
Lane 1 : Human spleen tissue lysate
Lane 2 : Human spleen tissue lysate with blocking peptide
Predicted band size: 38 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABIN3 antibody (ab113748)ab113748, at 5 µg/ml, staining ABIN3 in formalin fixed, paraffin embedded, Human adrenal tissue by Immunohistochemistry
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab113748 は 2 報の論文で使用されています。
- Wang X et al. The Imbalance of Mitochondrial Homeostasis of Peripheral Blood-Derived Macrophages Mediated by MAFLD May Impair the Walking Ability of Elderly Patients with Osteopenia. Oxid Med Cell Longev 2022:5210870 (2022). PubMed: 35368864
- Liu D et al. TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation. Cell Metab 31:726-740.e8 (2020). PubMed: 32268115