Anti-ABCB6/PRP 抗体 (ab47837)
Key features and details
- Rabbit polyclonal to ABCB6/PRP
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ABCB6/PRP antibody
ABCB6/PRP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ABCB6/PRP -
由来種
Rabbit -
特異性
A BLAST analysis was used to suggest cross reactivity with ABCB6 protein from human and dog based on 100% homology with the immunizing sequence. Expect partial reactivity with ABCB6 from mouse and rat sources based on partial (~93%, 15/16) sequence homology. Reactivity against homologues from other sources is not known.
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アプリケーション
適用あり: WB, ELISAmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide corresponding to Human ABCB6/PRP aa 440-455 (internal sequence).
Sequence:RAMNTQENATRARAVD
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ポジティブ･コントロール
- KB cells transfected with the ABCB6/PRP protein.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.01% Sodium azide
Constituents: 0.424% Tripotassium orthophosphate, 0.88% Sodium chloride -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
This affinity-purified antibody is directed against human ABCB6 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab47837の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | ||
| ELISA |
| 特記事項 |
|---|
IF (microscopy): Use at an assay dependent dilution.
WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. -
組織特異性
Widely expressed. Highest expression in heart and skeletal muscles. -
配列類似性
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain. -
発生段階
Highly expressed in fetal liver. -
細胞内局在
Mitochondrion outer membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 10058 Human
- Entrez Gene: 74104 Mouse
- Entrez Gene: 140669 Rat
- Omim: 605452 Human
- SwissProt: Q9NP58 Human
- SwissProt: Q9DC29 Mouse
- SwissProt: O70595 Rat
- Unigene: 107911 Human
see all -
別名
- ABC antibody
- ABC transporter umat antibody
- ABC14 antibody
see all
画像
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Western blot - Anti-ABCB6/PRP antibody (ab47837)All lanes : Anti-ABCB6/PRP antibody (ab47837) at 1/1400 dilution
Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6/PRP protein
Lane 2 : KB cell lysate without a vector insert
Predicted band size: 93 kDa
Observed band size: 104 kDa why is the actual band size different from the predicted?
Additional bands at: 79 kDa (possible truncated form)
データシートおよび資料
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Datasheet download
参考文献 (0)
ab47837 は論文での使用が確認できていません。
