Anti-5HT1B Receptor 抗体 (ab85937)
Key features and details
- Rabbit polyclonal to 5HT1B Receptor
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-5HT1B Receptor antibody
5HT1B Receptor 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to 5HT1B Receptor -
由来種
Rabbit -
特異性
This antibody has been sucessfully used on rat tissue in IHC. Since the immunogen only shares 84% homology, customers may get variable results. Please see the abreview for more details. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee, Gorilla, Common marmoset
-
免疫原
Synthetic peptide corresponding to Human 5HT1B Receptor aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab94829) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab85937の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).
|
| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa). |
ターゲット情報
-
機能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
翻訳後修飾
Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation.
Palmitoylated. -
細胞内局在
Cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 462833 Chimpanzee
- Entrez Gene: 3351 Human
- Omim: 182131 Human
- SwissProt: P60020 Chimpanzee
- SwissProt: Q9N2B7 Gorilla
- SwissProt: P28222 Human
- Unigene: 123016 Human
-
別名
- 5 HT1DB antibody
- 5 hydroxytryptamine receptor 1B antibody
- 5-HT-1B antibody
see all
画像
-
Western blot - Anti-5HT1B Receptor antibody (ab85937)5HT1B Receptor antibody at 1 µg/ml + Human brain tissue lysate - total protein (ab29466) at 10 µg
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 43 kDa
Observed band size: 43 kDa
Exposure time: 20 minutes
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab85937 は 1 報の論文で使用されています。
- Kratz A et al. Digital expression profiling of the compartmentalized translatome of Purkinje neurons. Genome Res 24:1396-410 (2014). PubMed: 24904046