Anti-5HT1B Receptor 抗体 (ab13896)
Key features and details
- Rabbit polyclonal to 5HT1B Receptor
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-5HT1B Receptor antibody
5HT1B Receptor 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to 5HT1B Receptor -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: IHC-Fr or IHC-P -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Rat 5HT1B Receptor. 8-26(CAPPPPATSQTGVPLANLS) and 263-278(VTSINSRVPEVPSESG)
Database link: P28564 -
ポジティブ・コントロール
- WB: Human brain lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
This antibody is affinity purified. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab13896の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 40-41 kDa (predicted molecular weight: 47 kDa).
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 40-41 kDa (predicted molecular weight: 47 kDa). |
ターゲット情報
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機能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
翻訳後修飾
Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation.
Palmitoylated. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3351 Human
- Entrez Gene: 15551 Mouse
- Entrez Gene: 25075 Rat
- Omim: 182131 Human
- SwissProt: P28222 Human
- SwissProt: P28334 Mouse
- SwissProt: P28564 Rat
- Unigene: 123016 Human
see all -
別名
- 5 HT1DB antibody
- 5 hydroxytryptamine receptor 1B antibody
- 5-HT-1B antibody
see all
画像
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Western blot analysis of 5HT1B Receptor in human brain lysate with ab13896. A protein band of approximate molecular weight of 40-41kDa was detected. Western blot analysis of 5HT1B Receptor in human brain lysate with ab13896. A protein band of approximate molecular weight of 40-41kDa was detected.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (20)
ab13896 は 20 報の論文で使用されています。
- Jung JW et al. Dopamine and serotonin alterations by Hizikia fusiformis extracts under in vitro cortical primary neuronal cell cultures. Nutr Res Pract 17:408-420 (2023). PubMed: 37266125
- Edvinsson JCA et al. Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptors. J Headache Pain 23:26 (2022). PubMed: 35177004
- Song JH et al. Improvement Effects of Myelophil on Symptoms of Chronic Fatigue Syndrome in a Reserpine-Induced Mouse Model. Int J Mol Sci 22:N/A (2021). PubMed: 34638540
- Pu ZH et al. Alkaloids from the rhizomes of Ligusticum striatum exert antimigraine effects through regulating 5-HT1B receptor and c-Jun. J Ethnopharmacol 237:39-46 (2019). PubMed: 30880256
- Frederiksen SD et al. Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans. Neuroscience 393:319-332 (2018). PubMed: 30336190