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Mouse IL-6 ELISA Set (without plates) (ab47596)

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Murine IL-6 ELISA Set (ab47596)

    製品の概要

    • 製品名

      Mouse IL-6 ELISA Set (without plates)
      IL-6 キット 製品一覧

    • サンプルの種類

      Cell culture supernatant, Serum, Plasma

    • アッセイタイプ

      Sandwich (quantitative)

    • 検出感度

      < 10 pg/ml

    • 検出範囲

      15.6 pg/ml - 500 pg/ml

    • 全工程の試験時間

      3h 50m

    • ステップ

      Multiple steps standard assay

    • 種交差性

      交差種: Mouse

    • 製品の概要

      Abcam’s IL-6 Murine in vitro ELISA Set is designed for the quantitative measurement of Murine IL-6 in cell culture supernatants, buffered solutions, serum, plasma and other body fluids.


      This ELISA Set is intended to measure murine IL-6 in cell-culture supernatants, as well as in serum samples. The enclosed procedures provide general guidelines for ELISA preparation. This procedure may need some optimization depending on the plastic, matrix, standard range.


      The murine IL-6 ELISA Set includes both the capture and the detection antibodies as well as Horse-Radish peroxidase conjugated Streptavidin (HRP-Strep) and TMB which are the reagents used in the colour development step.


      Recognizes both natural and recombinant Murine IL6

    • アプリケーション

      適用あり: Sandwich ELISAmore details

    • 試験プラットフォーム

      Reagents

    製品の特性

    • 保存方法

      Store at +4°C. Please refer to protocols.
    • 内容 10 x 96 tests 15 x 96 tests 5 x 96 tests
      Chromogen TMB Substrate Solution 4 vials 6 vials 2 vials
      Detection biotinylated anti-murine IL-6 antibody 2 x 0.55ml 3 x 0.55ml 1 x 0.55ml
      Murine IL-6 Capture antibody 2 x 0.1ml 3 x 0.1ml 1 x 0.1ml
      Murine IL-6 standard 10 vials 15 vials 5 vials
      Streptavidin-HRP 2 vials 3 vials 1 vial

    • 研究分野

    • 機能

      Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

    • 関連疾患

      Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:604302]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
      Note=A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.

    • 配列類似性

      Belongs to the IL-6 superfamily.

    • 翻訳後修飾

      N- and O-glycosylated.

    • 細胞内局在

      Secreted.
    • Information by UniProt

    • 別名

      • Interleukin BSF 2
      • B cell differentiation factor
      • B cell stimulatory factor 2
      • B-cell stimulatory factor 2
      • BSF 2
      • BSF-2
      • BSF2
      • CDF
      • CTL differentiation factor
      • Cytotoxic T cell differentiation factor
      • Hepatocyte stimulating factor
      • Hepatocyte stimulatory factor
      • HGF
      • HSF
      • Hybridoma growth factor
      • Hybridoma growth factor Interferon beta-2
      • Hybridoma plasmacytoma growth factor
      • IFN-beta-2
      • IFNB2
      • IL 6
      • IL-6
      • IL6
      • IL6_HUMAN
      • Interferon beta 2
      • Interferon beta-2
      • Interleukin 6
      • Interleukin 6 (interferon beta 2)
      • Interleukin BSF 2
      • Interleukin-6
      see all

    • 参照データベース

      アプリケーション

      The Abpromise guarantee

      Abpromise保証は、 次のテスト済みアプリケーションにおけるab47596の使用に適用されます

      アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

      アプリケーション Abreviews 特記事項
      Sandwich ELISA
      Use at an assay dependent concentration.
      特記事項
      Sandwich ELISA
      Use at an assay dependent concentration.

      画像

      • Murine IL-6 ELISA Set (ab47596)
        Murine IL-6 ELISA Set (ab47596)

        Mouse IL-6 Standard curve ranging from 15.6 to 500 pg/mL

      参考文献 (0)

      ab47596 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab47596 は論文での使用が確認できていません。

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