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AB324257

Human INHBE ELISA Kit (Inhibin beta E)

Human INHBE ELISA Kit (Inhibin beta E)

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Human INHBE ELISA Kit (Inhibin beta E) (ab324257) is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of INHbE in human serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

別名を表示する

Inhibin beta E chain, Activin beta-E chain, INHBE

1 Images
Sandwich ELISA - Human INHBE ELISA Kit (Inhibin beta E) (AB324257)
  • sELISA

Supplier Data

Sandwich ELISA - Human INHBE ELISA Kit (Inhibin beta E) (AB324257)

In order to make the calculation easier, we plot the O.D. value of the standard (X-axis) against the log of concentration of the standard (Y-axis), although concentration is the independent variable and O.D. value is the dependent variable. The O.D. values of the standard curve may vary according to the conditions of assay performance (e.g. operator, pipetting technique, washing technique or temperature effects). Typical standard curve below is provided for reference only.

Key facts

サンプルタイプ

Serum, Plasma, Tissue Homogenate, Cell Lysate, Cell culture supernatant, Other biological fluids

交差種

Human

Quantitative
検出感度

= 1.7 pg/mL

検出範囲

4.8 - 3000 pg/mL

アッセイ時間

2h

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "cELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

製品の詳細

Human INHBE ELISA Kit (Inhibin beta E) (ab324257) is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of INHbE in human serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

精度

[ { "reproducibilityType": "Intra", "sample": "Sample", "replicates": 3, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 10" }, { "reproducibilityType": "Inter", "sample": "Sample", "replicates": 8, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 12" } ]

回収率

[ { "sample": "Serum", "range": "86 - 105 %", "average": "= 97" }, { "sample": "EDTA Plasma", "range": "90 - 101 %", "average": "= 94" }, { "sample": "Heparin Plasma", "range": "82 - 93 %", "average": "= 86" } ]

製品内容

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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Please refer to protocols

製品プロトコール

ターゲットの情報

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.. Activin E is a homodimer of INHBE secreted by the liver that plays a crucial role in regulating metabolic homeostasis particularly in lipid metabolism and energy homeostasis. Plays a central role in the regulation of adipose tissue lipolysis by preventing the influx of fatty acids from adipose tissue into the liver. Mechanistically, signals via ACVR1C to activate SMAD2/3 signaling, suppressing PPARG target genes in adipose tissue, thereby reducing liver lipid content and improving glycemic control (PubMed : 38533769). Induces beige adipocyte formation and thermogenesis in response to cold exposure (By similarity).
See full target information INHBE
websiteProtocolBooklet
en

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