AB309407

Human HAPLN1 ELISA Kit

Name: Human HAPLN1 ELISA Kit (ab309407) | Abcam
Brand: Abcam Limited
SKU: AB309407
Price: 135000 JPY
Availability: InStock

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Human HAPLN1 ELISA Kit is a Sandwich ELISA for the measurement of Human HAPLN1 in Human in Biofluids, Cell Culture Media samples.

別名を表示する

CRTL1, HAPLN1, Hyaluronan and proteoglycan link protein 1, Cartilage-linking protein 1, Proteoglycan link protein, Cartilage-link protein

1 Images

Sandwich ELISA - Human HAPLN1 ELISA Kit (AB309407)

sELISA

Supplier Data

Sandwich ELISA - Human HAPLN1 ELISA Kit (AB309407)

Example of standard curve using ab309407. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.

Key facts

検出方法

Colorimetric

サンプルタイプ

Plasma, Serum, Cell culture supernatant

交差種

Human

アッセイタイプ

Sandwich

検出感度

= 0.75 ng/mL

検出範囲

0.75 - 200 ng/mL

アッセイプラットフォーム

Pre-coated microplate (12 x 8 well strips)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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製品の詳細

Human HAPLN1 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CD42b in serum, plasma, and cell culture supernatants. This assay employs an antibody specific for human HAPLN1 coated on a 96-well plate.

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回収率

[ { "sample": "Serum", "range": "93 - 119 %", "average": "= 105.6" }, { "sample": "Plasma", "range": "79 - 100 %", "average": "= 88.85" }, { "sample": "Cell culture supernatant", "range": "90 - 117 %", "average": "= 102" }, { "sample": "Cell culture media", "range": "90 - 117 %", "average": "= 102" } ]

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製品内容

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出荷温度及び保存条件

出荷温度

Blue Ice

短期保存温度

-20°C

長期保存温度

-20°C

保管に関する情報

-20°C

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

HAPLN1 also known as hyaluronan and proteoglycan link protein 1 is an important structural component in the extracellular matrix. This protein links hyaluronan to proteoglycans which contributes to the integrity and function of the matrix. HAPLN1 has a molecular mass of approximately 39 kDa and is expressed in various tissues including cartilage and nervous tissues. Its expression plays a significant role in maintaining the properties of these tissues.

Biological function summary

Hyaluronan and proteoglycan link protein 1 supports the organization and stabilization of the extracellular matrix network. As part of this framework HAPLN1 forms complexes with hyaluronan and aggrecan ensuring structural stability and resilience in tissues experiencing mechanical stress. The association with such complexes impacts cellular signaling and tissue hydration which are important for maintaining tissue homeostasis and function.

Pathways

HAPLN1 participates in extracellular matrix organization and cell signaling processes. It is actively involved in the aggrecan pathway which influences cartilage development and repair. HAPLN1 is also connected to proteins like aggrecan and link proteins that help mediate interactions within the matrix and regulate cellular responses to mechanical stress.

Abnormal expression or function of HAPLN1 has links to osteoarthritis and intervertebral disc degeneration. In these conditions the disruption of extracellular matrix composition alters tissue integrity and function. An imbalance involving HAPLN1 along with proteins like aggrecan contributes to the pathogenesis and progression of these disorders affecting joint and disc health.

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製品プロトコール

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ターゲットの情報

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

See full target information HAPLN1

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websiteProtocolBooklet

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Abcam product promise

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Human HAPLN1 ELISA Kit