Human OCIAD1 knockout HEK-293T cell lysate
Human OCIAD1 knockout HEK-293T cell lysate
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OCIAD1 KO cell lysate available now. KO validated. Free of charge wild type control included. Knockout achieved by using CRISPR/Cas9, Homozygous: 5 bp deletion in exon 2.
別名を表示する
Asrij, FLJ20455, MGC111072, OCAD1_HUMAN, OCIA, OCIA domain containing 1, OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen, TPA018
- Sanger seq
Unknown
Sanger Sequencing - Human OCIAD1 knockout HEK-293T cell lysate (AB258552)
Homozygous : 5 bp deletion in exon 2
製品の詳細
Knockout cell lysate achieved by CRISPR/Cas9.
REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.
Lysate preparation: Our lysates are made using RIPA buffer to which we add a protease inhibitor cocktail and phosphatase inhibitor cocktail (ratio: 300:100:10). This means that the protein of interest is denatured. If you require a native form of the protein please use the live cell version. Please refer to our lysis protocol for further details on how our lysates are prepared.
User storage instructions: Lyophilizate may be stored at 4°C. After reconstitution, store at -20°C for short-term storage or -80°C for long-term storage.
This product is subject to limited use licenses from The Broad Institute and ERS Genomics Limited, and is developed with patented technology. For full details of the limited use licenses and relevant patents please refer to our limited use license and patent pages.
製品内容
出荷温度及び保存条件
遺伝子名
遺伝子編集のタイプ
遺伝子編集の方法
ノックアウト検証方法
接合型
出荷温度
短期保存温度
長期保存温度
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
OCIAD1 engages in cellular signaling and regulation. It might be a part of a protein complex that contributes to cellular adhesion and proliferation. OCIAD1 appears to support cellular growth and may steer certain cell developmental pathways. By interacting with other proteins it could modulate cellular response mechanisms suggesting its importance in maintaining normal cellular function.
Pathways
OCIAD1 plays roles that impact the PI3K/AKT signaling pathway and the MAPK/ERK pathway. These pathways are essential for the regulation of cell survival growth and differentiation. Within these networks OCIAD1 may interact with proteins like AKT1 and ERK2 facilitating signal transduction that drives cellular responses. Its involvement in these pathways indicates a role in the modulation of critical intracellular signaling events.
Quality control
STR analysis
CSF1PO, D13S317, D7S820, D5S818, TH01, D16S539, TPOX
Cell culture
Biosafety level
EU: 2 US: 2
Adherent/suspension
Adherent
Gender
Female
Abcam product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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