Verteporfin (Visudyne), Benzoporphyrin derivative (ab143294)
Key features and details
- Benzoporphyrin derivative. Antiangiogenic agent.
- CAS Number: 129497-78-5
- Purity: > 96%
- Soluble in DMSO to 100 mg/ml
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Verteporfin (Visudyne), Benzoporphyrin derivative -
製品の詳細
Benzoporphyrin derivative. Antiangiogenic agent. -
生理活性の詳細
Benzoporphyrin derivative. Antiangiogenic agent. Produces ROS on stimulation with nonthermal red light in the presence of oxygen. Prevents corneal neovascularization and shows antitumor effects in vivo. -
精製度
> 96% -
CAS 番号
129497-78-5 -
構造式
製品の特性
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体系名
(4S,4aR)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester -
分子量
718.79 -
分子式
C41H42N4O8 -
PubChem 登録番号
5362420 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mg/ml -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5[C@@]6([C@@H](C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C -
由来
Synthetic
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研究分野
画像
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Chemical Structure - Verteporfin (Visudyne), Benzoporphyrin derivative (ab143294)2D chemical structure image of ab143294, Verteporfin (Visudyne), Benzoporphyrin derivative
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab143294 は 2 報の論文で使用されています。
- Chen C et al. FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer. Breast Cancer Res Treat 201:515-533 (2023). PubMed: 37458908
- Carbonell M B et al. Hydrogen peroxide is necessary during tail regeneration in juvenile axolotl. Dev Dyn 251:1054-1076 (2022). PubMed: 34129260
