Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online

Tiron, superoxide scavenger and antioxidant (ab146234)

Reviews (1) Submit a question References (4)
Chemical Structure - Tiron, superoxide scavenger and antioxidant (ab146234)

    Key features and details

    • Cell permeable superoxide scavenger and antioxidant.
    • CAS Number: 149-45-1
    • Soluble in water
    • Form / State: Solid
    • Source: Synthetic

    製品の概要

    • 製品名

      Tiron, superoxide scavenger and antioxidant

    • 製品の詳細

      Cell permeable superoxide scavenger and antioxidant.

    • 別名

      • 4,5-Dihydroxy-1,3-benzenedisulfonic acid disodium salt
      • Disodium-1,2-dihydroxybenzene-3,5-disulfonate
      • Pyrocatechol-3,5-disulfonic acid disodium salt
      • Sodium catechol sulfate
      • Tiferron
      see all

    • CAS 番号

      149-45-1

    • 構造式

      Chemical Structure

    製品の特性

    • 体系名

      4,5-Dihydroxy-1,3-benzenedisulfonic acid disodium salt

    • 分子量

      314.20

    • 分子式

      C6H4Na2O8S2

    • PubChem 登録番号

      9001

    • 保存方法

      Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.

    • 溶解性

      Soluble in water

    • 使用に関する注意

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Refer to SDS for further information.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES 線形表記

      C1=C(C=C(C(=C1O)O)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+]

    • 由来

      Synthetic

    画像

    • Chemical Structure - Tiron, superoxide scavenger and antioxidant (ab146234)
      Chemical Structure - Tiron, superoxide scavenger and antioxidant (ab146234)
      2D chemical structure image of ab146234, Tiron, superoxide scavenger and antioxidant

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (4)

    ab146234 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab146234 は 4 報の論文で使用されています。

    • Frara N  et al. Mechanisms involved in nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox)-derived reactive oxygen species (ROS) modulation of muscle function in human and dog bladders. PLoS One 18:e0287212 (2023). PubMed: 37352265
    • Zhu X  et al. ZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection. Cell Rep 41:111540 (2022). PubMed: 36243002
    • Peng X  et al. Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy. J Exp Clin Cancer Res 40:374 (2021). PubMed: 34844627
    • Skinner SC  et al. Increased Prevalence of Type 2 Diabetes-Related Complications in Combined Type 2 Diabetes and Sickle Cell Trait. Diabetes Care 41:2595-2602 (2018). PubMed: 30327363

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Great compound for superoxide scavenger and antioxidant

     Good
    Abreviews
    It is a water soluble compound that can be treated with the cells to study for oxidative stress.
    The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

    Abcam user community

    Verified customer

    投稿 Nov 15 2021

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
    For licensing inquiries, please contact partnerships@abcam.com