Tandospirone hydrochloride (Metanopirone), 5-HT1A partial agonist (ab146136)
Key features and details
- Potent, selective 5-HT1A partial agonist
- CAS Number: 99095-10-0
- Purity: > 99%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Tandospirone hydrochloride (Metanopirone), 5-HT1A partial agonist -
製品の詳細
Potent, selective 5-HT1A partial agonist -
生理活性の詳細
Potent, selective 5-HT1A partial agonist (Ki = 27 nM). Decreases the firing rate of 5-HT neurons of the dorsal raphe. Shows anxiolytic and antidepressant effects in vivo. Orally active.
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精製度
> 99% -
CAS 番号
99095-10-0 -
構造式
製品の特性
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体系名
(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride -
分子量
419.95 -
分子式
C21H29N5O2.HCl -
PubChem 登録番号
13422623 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1C[C@H]2C[C@@H]1[C@H]3[C@@H]2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5.Cl -
由来
Synthetic
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研究分野
画像
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Chemical Structure - Tandospirone hydrochloride (Metanopirone), 5-HT1A partial agonist (ab146136)2D chemical structure image of ab146136, Tandospirone hydrochloride (Metanopirone), 5-HT1A partial agonist
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab146136 は論文での使用が確認できていません。
