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AB120386

Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor

Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor

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(2 Publications)

MW 183.91 g/mol. Broad spectrum inhibitor of protein tyrosine phosphatases. Also inhibits ATPases. Inhibits apoptosis. Chemical precursor to decavanadate, which is formed at acidic pH; inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding.
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Chemical Structure - Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor (AB120386)
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Chemical Structure - Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor (AB120386)

2D chemical structure image of ab120386, Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor

Key facts

CAS番号

13721-39-6

製品の状態

Solid

form

分子量

183.91 g/mol

分子式

Na<sub>3</sub>VO<sub>4</sub>

由来

Synthetic

溶解性

Soluble in water to 100 mM

生物学的記述

Broad spectrum inhibitor of protein tyrosine phosphatases. Also inhibits ATPases. Inhibits apoptosis. Chemical precursor to decavanadate, which is formed at acidic pH; inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding.

InChiKey

HQHUIUQMQXUPHI-UHFFFAOYSA-N

IUPAC名

Sodium orthovanadate

出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
Ambient
長期保存温度
Ambient
保管に関する情報
The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

製品プロトコール

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cellular and infection microbiology 14:1374659 PubMed38524184

2024

infection-induced host cellular DNA damage is strain-dependent and leads to the activation of the ATM-dependent homologous recombination pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lisbeth Rojas-Barón,Carlos Hermosilla,Anja Taubert,Zahady D Velásquez

Frontiers in microbiology 15:1336267 PubMed38450167

2024

Me49 and NED strains arrest host cell cycle progression and alter chromosome segregation in a strain-independent manner.

Applications

Unspecified application

Species

Unspecified reactive species

Lisbeth Rojas-Barón,Carlos Hermosilla,Anja Taubert,Zahady D Velásquez
View all publications

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