SF1670, PTEN inhibitor (ab141303)
Key features and details
- Selective PTEN inhibitor
- CAS Number: 345630-40-2
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
SF1670, PTEN inhibitor -
製品の詳細
Selective PTEN inhibitor -
別名
- PTP Inhibitor XIX
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精製度
> 98% -
CAS 番号
345630-40-2 -
構造式
製品の特性
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体系名
N-(9,10-Dioxophenanthren-2-yl)-2,2-dimethylpropanamide -
分子量
307.35 -
分子式
C19H17NO3 -
PubChem 登録番号
9926586 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC(C)(C)C(=O)Nc1ccc2c(c1)C(=O)C(=O)c3ccccc23 -
由来
Synthetic
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研究分野
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
画像
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Chemical Structure - SF1670, PTEN inhibitor (ab141303)2D chemical structure image of ab141303, SF1670, PTEN inhibitor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (5)
ab141303 は 5 報の論文で使用されています。
- Ha SE et al. Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NF-?B Signaling through PTEN Activation in Hepatocellular Carcinoma. Int J Mol Sci 22:N/A (2021). PubMed: 34445559
- Wang P et al. Inhibition of microRNA-149 protects against recurrent miscarriage through upregulating RUNX2 and activation of the PTEN/Akt signaling pathway. J Obstet Gynaecol Res N/A:N/A (2020). PubMed: 32939872
- Xu F et al. Pectolinarigenin inhibits non-small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathway. Oncol Rep 40:3458-3468 (2018). PubMed: 30542737
- Pan YG et al. FceRI ?-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells. Front Immunol 8:1424 (2017). PubMed: 29163499
- Kälin S et al. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. Cell Metab 26:475-492.e7 (2017). PubMed: 28877454