SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor (ab142221)
Key features and details
- Methyl donor and cofactor for enzyme-catalyzed methylations
- CAS Number: 97540-22-2
- Purity: > 95%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor -
製品の詳細
Methyl donor and cofactor for enzyme-catalyzed methylations -
精製度
> 95% -
特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 2077 S-Adenosyl-L-methionine disulfate tosylate. 2077-100 is the same size as the 100 mg size of ab142221.
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CAS 番号
97540-22-2 -
構造式
製品の特性
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体系名
[(3S)-3-Amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methyl]methylsulfanium disulfate tosylate -
分子量
766.78 -
分子式
C15H22N6O5S.C7H8O3S.2H2SO4 -
PubChem 登録番号
163657 -
保存方法
Shipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.OS(=O)(=O)[O-].[O-]S(=O)(=O)[O-] -
由来
Synthetic
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研究分野
画像
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Chemical Structure - SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor (ab142221)2D chemical structure image of ab142221, SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab142221 は 4 報の論文で使用されています。
- Wang H et al. Excitatory Effects of Astrocytic Hydrogen Sulfide on the Electrical Activity of Oxytocin Neurons in the Supraoptic Nucleus. Neuroendocrinology 113:343-360 (2023). PubMed: 36044869
- Admoni-Elisha L et al. TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma. Nucleic Acids Res 50:6903-6918 (2022). PubMed: 35694846
- Pan Y et al. METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma. J Clin Invest 132:N/A (2022). PubMed: 36099048
- Vershinin Z et al. BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Sci Adv 7:N/A (2021). PubMed: 34039605