RK-682, protein tyrosine phosphatase (PTP) inhibitor (ab141730)
Key features and details
- Potent, selective and competitive protein tyrosine phosphatase (PTP) inhibitor
- CAS Number: 154639-24-4
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
RK-682, protein tyrosine phosphatase (PTP) inhibitor -
製品の詳細
Potent, selective and competitive protein tyrosine phosphatase (PTP) inhibitor -
生理活性の詳細
Potent, selective and competitive protein tyrosine phosphatase (PTP) inhibitor (IC50 values are 5.5, 54 and 2-11.6 μM at PTP1B, CD45 and VHR respectively). Inhibits cell cycle progression at G1/S transition. -
精製度
> 98% -
CAS 番号
154639-24-4 -
構造式
製品の特性
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体系名
(2R)-4-Hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one -
分子量
368.50 -
分子式
C21H36O5 -
PubChem 登録番号
54678922 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 50 mM and in ethanol to 25 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCCCCCCCCCCCCCCC(=O)C1=C(C(OC1=O)CO)O -
由来
Synthetic
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研究分野
画像
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Chemical Structure - RK-682, protein tyrosine phosphatase (PTP) inhibitor (ab141730)2D chemical structure image of ab141730, RK-682, protein tyrosine phosphatase (PTP) inhibitor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab141730 は 1 報の論文で使用されています。
- Kase Y et al. The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization. iScience 25:104089 (2022). PubMed: 35497000
