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AB145725

Probenecid, ABC-transporter inhibitor

Probenecid, ABC-transporter inhibitor

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(1 Publication)

MW 285.36 Da, Purity >98%. ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.

別名を表示する

CA 12, CA 2, CA-II, CA-IX, CA-XII, CA9, CAC, CAH12_HUMAN, CAH2_HUMAN, CAH9_HUMAN, Car 2, Carbonate dehydratase II, Carbonate dehydratase IX, Carbonate dehydratase XII, Carbonic anhydrase 12, Carbonic anhydrase 2, Carbonic anhydrase 9, Carbonic anhydrase B, Carbonic anhydrase C, Carbonic anhydrase C, formerly, Carbonic anhydrase II, Carbonic anhydrase IX, Carbonic anhydrase XII, Carbonic dehydratase, Epididymis secretory protein Li 282, FLJ20151, HEL-76, HEL-S-282, HsT18816, MN, Membrane antigen MN, P54/58N, RCC associated protein G250, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250, T18816, Tumor antigen HOM-RCC-3.1.3, epididymis luminal protein 76, pMW1

1 Images
Chemical Structure - Probenecid, ABC-transporter inhibitor (AB145725)
  • Chemical Structure

Lab

Chemical Structure - Probenecid, ABC-transporter inhibitor (AB145725)

2D chemical structure image of ab145725, Probenecid, ABC-transporter inhibitor

Key facts

CAS番号

57-66-9

精製度

>98%

製品の状態

Solid

form

分子量

285.36 Da

分子式

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>9</sub>NO<sub>4</sub>S

PubChem

4911

由来

Synthetic

溶解性

Soluble in ethanol to 75 mM

Soluble in DMSO to 100 mM

化学名

Probenecid

生物学的記述

ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.

Canonical smiles

CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O

InChi

InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)

InChiKey

DBABZHXKTCFAPX-UHFFFAOYSA-N

IUPAC名

4-(dipropylsulfamoyl)benzoic acid

出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Store under desiccating conditions|The product can be stored for up to 12 months

製品プロトコール

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cell reports 22:3416-3426 PubMed29590612

2018

A Conserved Circadian Function for the Neurofibromatosis 1 Gene.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Bai,Yool Lee,Cynthia T Hsu,Julie A Williams,Daniel Cavanaugh,Xiangzhong Zheng,Carly Stein,Paula Haynes,Han Wang,David H Gutmann,Amita Sehgal
View all publications

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