p-Nitropifithrin-alpha, p53 inhibitor (ab145873)
Key features and details
- Cell-permeable p53 inhibitor
- CAS Number: 389850-21-9
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
p-Nitropifithrin-alpha, p53 inhibitor -
製品の詳細
Cell-permeable p53 inhibitor -
生理活性の詳細
Cell-permeable p53 inhibitor. Pifithrin-α (ab120478) analog and prodrug. Shows more potent antiapoptotic effects than pifithrin-α. Shows antiobesogenic and hepatoprotective effects in vivo.
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精製度
> 98% -
特記事項
It is important to note that this product has been reported to be unstable under a variety of conditions. In addition to being unstable to light and air after extended periods of time, this product is extremely unstable in polar solvents such as DMSO. Within 6 hours a DMSO solution had been found to be completely converted into the tricyclic material. We therefore recommend this material is only stored as the solid form at -20°C (or below), with the exclusion of light and air, and any solutions are made up fresh and used immediately.
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CAS 番号
389850-21-9 -
構造式
製品の特性
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体系名
1-(4-Nitrophenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide -
分子量
398.27 -
分子式
C15H15N3O3S.HBr -
PubChem 登録番号
11553038 -
保存方法
Store at -20°C. Please see notes section. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1CCC2=C(C1)N(C(=N)S2)CC(=O)C3=CC=C(C=C3)[N+](=O)[O-].Br -
由来
Synthetic
画像
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Chemical Structure - p-Nitropifithrin-alpha, p53 inhibitor (ab145873)2D chemical structure image of ab145873, p-Nitropifithrin-alpha, p53 inhibitor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab145873 は論文での使用が確認できていません。
