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AB145219

N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone

N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone

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N-Palmitoyl phosphatidylethanolamine (CAS No: 108321-22-8)(ab145219). Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity. MW 930.4. Purity >98%.

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1 Images
Chemical Structure - N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone (AB145219)
  • Chemical Structure

Lab

Chemical Structure - N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone (AB145219)

2D chemical structure image of ab145219, N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone

Key facts

CAS番号

108321-22-8

精製度

>98%

分子量

930.4 g/mol

分子式

C<sub>5</sub><sub>3</sub>H<sub>1</sub><sub>0</sub><sub>4</sub>NO<sub>9</sub>P

由来

Synthetic

生物学的記述

Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.

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組合せ製品

Assay Kits

AB83431

Alpha Ketoglutarate (alpha KG) Assay Kit

Functional Studies - Alpha Ketoglutarate (alpha KG) Assay Kit (AB83431)

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Assay Kits

AB83390

beta Hydroxybutyrate (beta HB) Assay Kit (Colorimetric)

Functional Studies - beta Hydroxybutyrate (beta HB) Assay Kit (Colorimetric) (AB83390)

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Biochemicals

AB141137

Imiloxan hydrochloride, alpha2B adrenoceptor antagonist

Chemical Structure - Imiloxan hydrochloride, alpha2B adrenoceptor antagonist (AB141137)

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Biochemicals

AB218603

AC 55541, protease-activated receptor 2 (PAR2) agonist

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出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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製品プロトコール

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