MMP-9 inhibitor (ab142180)
Key features and details
- MMP-9 inhibitor
- CAS Number: 1177749-58-4
- Purity: > 95%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
MMP-9 inhibitor -
生理活性の詳細
MMP-9 inhibitor. Role in tumor cell migration, invasion and angiogenesis -
精製度
> 95% -
特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 1981 MMP-9 Inhibitor. 1981-500 is the same size as the 500 µg size of ab142180.
-
CAS 番号
1177749-58-4 -
構造式
製品の特性
-
体系名
2-(N-Benzyl-4-methoxyphenylsulfonamido)-5-((diethylamino)methyl)-N-hydroxy-3-methylbenzamide -
分子量
511.63 -
分子式
C27H33N3O5S -
PubChem 登録番号
21310926 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 10 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES 線形表記
CCN(CC)CC1=CC(=C(C(=C1)C(=O)NO)N(CC2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)OC)C -
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (17)
ab142180 は 17 報の論文で使用されています。
- Tsukamoto S et al. Matrix Metalloproteinase 9 Induced in Esophageal Squamous Cell Carcinoma Cells via Close Contact with Tumor-Associated Macrophages Contributes to Cancer Progression and Poor Prognosis. Cancers (Basel) 15:N/A (2023). PubMed: 37296952
- Bzioueche H et al. Ceramide AD™ Restores Skin Integrity and Function following Exposure to House Dust Mite. Int J Mol Sci 24:N/A (2023). PubMed: 37298186
- Jouida A et al. Exosomes from EGFR-Mutated Adenocarcinoma Induce a Hybrid EMT and MMP9-Dependant Tumor Invasion. Cancers (Basel) 14:N/A (2022). PubMed: 35954442
- Zhang D et al. Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome by protecting against glycocalyx damage and suppressing inflammatory signaling pathways. Inflamm Res 69:267-278 (2020). PubMed: 31925528
- Boukhedouni N et al. Type-1 cytokines regulate MMP-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo. JCI Insight 5:N/A (2020). PubMed: 32369451
