ML130, NOD1 inhibitor (ab142177)
Key features and details
- Potent, selective, cell-permeable NOD1 inhibitor
- CAS Number: 799264-47-4
- Purity: > 97%
- Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
ML130, NOD1 inhibitor -
製品の詳細
Potent, selective, cell-permeable NOD1 inhibitor -
精製度
> 97% -
特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 1974 ML130. 1974-25 is the same size as the 25 mg size of ab142177.
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CAS 番号
799264-47-4 -
構造式
製品の特性
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体系名
1-(4-Methylphenyl)sulfonylbenzimidazol-2-amine -
分子量
287.34 -
分子式
C14H13N3O2S -
PubChem 登録番号
1088438 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 10 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=C2N -
由来
Synthetic
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研究分野
画像
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Chemical Structure - ML130, NOD1 inhibitor (ab142177)2D chemical structure image of ab142177, ML130, NOD1 inhibitor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab142177 は 2 報の論文で使用されています。
- Wu J et al. Peptidoglycan-Mediated Bone Marrow Autonomic Neuropathy Impairs Hematopoietic Stem/Progenitor Cells via a NOD1-Dependent Pathway in db/db Mice. Stem Cells Int 2022:4249843 (2022). PubMed: 35966130
- Liu FY et al. The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats. Med Sci Monit 26:e924748 (2020). PubMed: 32855380