JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB146175

ML-324, JMJD2 inhibitor

ML-324, JMJD2 inhibitor

Be the first to review this product! Submit a review

|

(0 Publication)

MW 349.4 Da. Potent, cell-permeable JMJD2 inhibitor (IC50 = 920 nM). Shows antiviral effects (IC50 = 10 μM), HSV-1 immediate early gene expression). Reversibly blocks human cytomegalovirus infection in vivo. .
1 Images
Chemical Structure - ML-324, JMJD2 inhibitor (AB146175)
  • Chemical Structure

Lab

Chemical Structure - ML-324, JMJD2 inhibitor (AB146175)

2D chemical structure image of ab146175, ML-324, JMJD2 inhibitor

Key facts

CAS番号

1222800-79-4

製品の状態

Solid

form

分子量

349.4 Da

分子式

C<sub>2</sub><sub>1</sub>H<sub>2</sub><sub>3</sub>N<sub>3</sub>O<sub>2</sub>

PubChem

44143209

由来

Synthetic

溶解性

Soluble in ethanol to 10 mM

Soluble in DMSO to 50 mM

化学名

N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide

生物学的記述

Potent, cell-permeable JMJD2 inhibitor (IC50 = 920 nM). Shows antiviral effects (IC50 = 10 μM), HSV-1 immediate early gene expression). Reversibly blocks human cytomegalovirus infection in vivo.

Canonical smiles

CN(C)CCCNC(=O)C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)O

InChi

InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26)

InChiKey

QDBVSOZTVKXUES-UHFFFAOYSA-N

IUPAC名

N-[3-(dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide

style
left-column

組合せ製品

Biochemicals

AB146156

BC-11-38, PDE-11 inhibitor

Chemical Structure - BC-11-38, PDE-11 inhibitor (AB146156)

  • 0
  • 0
Biochemicals

AB144689

MeIQx, Mutagenic agent

  • 0
  • 0
Biochemicals

AB120923

Leelamine, Pyruvate dehydrogenase kinase (PDK) inhibitor

Chemical Structure - Leelamine, Pyruvate dehydrogenase kinase (PDK) inhibitor (AB120923)

  • 0
  • 0
Biochemicals

AB142049

AZD1152-HQPA, Aurora B kinase inhibitor

Chemical Structure - AZD1152-HQPA, Aurora B kinase inhibitor (AB142049)

  • 0
  • 0
style
left-column
style
left-column

出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
Ambient
長期保存温度
Ambient
保管に関する情報
The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

|

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

|

Refer to SDS for further information.

style
left-column
style
left-column
style
left-column

製品プロトコール

style
left-column
style
left-column
style
right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com