LY255283, BLT2 receptor antagonist (ab144472)
Key features and details
- Selective, competitive BLT2 receptor antagonist
- CAS Number: 117690-79-6
- Purity: > 98%
- Soluble in ethanol to 25 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
LY255283, BLT2 receptor antagonist -
製品の詳細
Selective, competitive BLT2 receptor antagonist -
生理活性の詳細
Selective, competitive BLT2 receptor antagonist (IC50 values are 1 and 10 μM for BLT2 and BLT1 respectively). Shows antiasthmatic effects in vivo. Orally active. -
精製度
> 98% -
CAS 番号
117690-79-6 -
構造式
製品の特性
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体系名
1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone -
分子量
360.50 -
分子式
C19H28N4O3 -
PubChem 登録番号
122023 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 25 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCC1=C(C=C(C(=C1)C(=O)C)O)OCCCCCC(C)(C)C2=NNN=N2 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab144472 は 1 報の論文で使用されています。
- Lewis A & Elks PM Hypoxia Induces Macrophage tnfa Expression via Cyclooxygenase and Prostaglandin E2 in vivo. Front Immunol 10:2321 (2019). PubMed: 31611882
