Luffariellolide, phospholipase A2 (PLA2) inhibitor. Agonist at RARalpha (ab141759)
Key features and details
- Potent phospholipase A2 (PLA2) inhibitor. Agonist at RARα
- CAS Number: 111149-87-2
- Purity: > 98%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Luffariella sp.
製品の概要
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製品名
Luffariellolide, phospholipase A2 (PLA2) inhibitor. Agonist at RARalpha -
製品の詳細
Potent phospholipase A2 (PLA2) inhibitor. Agonist at RARα -
生理活性の詳細
Potent, partially reversible phospholipase A2 (PLA2) inhibitor (IC50 = 5 µM). Also a novel RARα agonist (EC50 = 1 μM). Derivative of marine sponge Luffariella sp. Displays anti-inflammatory activity and active in vivo. -
精製度
> 98% -
CAS 番号
111149-87-2 -
構造式
製品の特性
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体系名
3-[(3E,7E)-4,8-Dimethyl-10-(2,6,6-trimethylcyclohexen-1-yl)deca-3,7-dienyl]-2-hydroxy-2H-furan-5-one -
分子量
386.57 -
分子式
C25H38O3 -
PubChem 登録番号
5387248 -
保存方法
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
溶解性
Soluble in DMSO and in ethanol -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1=C(C(CCC1)(C)C)CCC(=CCCC(=CCCC2=CC(=O)OC2O)C)C -
由来
Luffariella sp.
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研究分野
画像
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Chemical Structure - Luffariellolide, phospholipase A2 (PLA2) inhibitor. Agonist at RARalpha (ab141759)2D chemical structure image of ab141759, Luffariellolide, phospholipase A2 (PLA2) inhibitor. Agonist at RARalpha
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab141759 は論文での使用が確認できていません。
