GW1929, PPARgamma agonist (ab142213)
Key features and details
- Potent, selective PPARγ agonist
- CAS Number: 196808-24-9
- Purity: > 98%
Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
GW1929, PPARgamma agonist -
製品の詳細
Potent, selective PPARγ agonist -
生理活性の詳細
Potent, selective PPARγ agonist (EC50 = 8 nM). Decreases glucose, fatty acid and triglyceride levels in vivo. Orally active.
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精製度
> 98% -
特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 2057 GW1929. 2057-25 is the same size as the 25 mg size of ab142213.
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CAS 番号
196808-24-9 -
構造式
製品の特性
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体系名
(2S)-2-(2-Benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid
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分子量
495.57 -
PubChem 登録番号
6518171 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4 -
由来
Synthetic
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研究分野
画像
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Chemical Structure - GW1929, PPARgamma agonist (ab142213)2D chemical structure image of ab142213, GW1929, PPARgamma agonist
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab142213 は 2 報の論文で使用されています。
- Shoaito H et al. The Role of Peroxisome Proliferator–Activated Receptor Gamma (PPAR?) in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation. Environ Health Perspect 127:27003 (2019). PubMed: 30810372
- Degrelle SA et al. New Transcriptional Reporters to Quantify and Monitor PPAR?Activity. PPAR Res 2017:6139107 (2017). PubMed: 29225614
