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AB142213

GW1929, PPARgamma agonist

GW1929, PPARgamma agonist

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(2 Publications)

MW 495.6 Da, Purity >98%. Potent, selective PPARγ agonist (EC50 = 8 nM). Decreases glucose, fatty acid and triglyceride levels in vivo. Orally active.

別名を表示する

ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, CP2D6_HUMAN, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, Cholesterol 25-hydroxylase, Class E basic helix-loop-helix protein 78, Cytochrome P450 2D6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450-DB1, D-OR-1, Debrisoquine 4-hydroxylase, Delta type opioid receptor DOR 1, Delta-type opioid receptor, HIF-1, HIF-1-alpha, HIF-alpha, HIF1A_HUMAN, Hypoxia inducible factor 1 alpha isoform I.3, Hypoxia inducible factor 1 alpha subunit, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor, Hypoxia inducible factor 1, alpha subunit (basic helix loop helix transcription factor), Hypoxia-inducible factor 1-alpha, MOP 1, Member of PAS protein 1, Member of PAS superfamily 1, Member of the PAS Superfamily 1, Microsomal monooxygenase, NR1C3, Nbor, Nuclear receptor subfamily 1 group C member 3, OPRD 1, OPRD_HUMAN, Opioid receptor delta 1, P450 DB1, P450C2D, PAS domain-containing protein 8, PASD 8, PPAR-gamma, PPARG2, PPARG_HUMAN, Peroxisome proliferator activated receptor gamma 2, Peroxisome proliferator-activated receptor gamma, Xenobiotic monooxygenase, bHLHe78, flavoprotein-linked monooxygenase, hifla, mDOR

1 Images
Chemical Structure - GW1929, PPARgamma agonist (AB142213)
  • Chemical Structure

Lab

Chemical Structure - GW1929, PPARgamma agonist (AB142213)

2D chemical structure image of ab142213, GW1929, PPARgamma agonist

Key facts

CAS番号

196808-24-9

精製度

>98%

製品の状態

Solid

form

分子量

495.6 Da

分子式

C<sub>3</sub><sub>0</sub>H<sub>2</sub><sub>9</sub>N<sub>3</sub>O<sub>4</sub>

PubChem

6518171

由来

Synthetic

溶解性

Soluble in DMSO

化学名

(S)-2-(2-benzoylphenylamino)-3-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)phenyl)propanoic acid

生物学的記述

Potent, selective PPARγ agonist (EC50 = 8 nM). Decreases glucose, fatty acid and triglyceride levels in vivo. Orally active.

Canonical smiles

CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4

Isomeric smiles

CN(CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4

InChi

InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27,32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1

InChiKey

QTQMRBZOBKYXCG-MHZLTWQESA-N

IUPAC名

(2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid

製品の詳細

This product is manufactured by BioVision, an Abcam company and was previously called 2057 GW1929. 2057-25 is the same size as the 25 mg size of ab142213.

出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Store under desiccating conditions|The product can be stored for up to 12 months

製品プロトコール

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Environmental health perspectives 127:27003 PubMed30810372

2019

The Role of Peroxisome Proliferator–Activated Receptor Gamma (PPARγ) in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Hussein Shoaito,Julia Petit,Audrey Chissey,Nicolas Auzeil,Jean Guibourdenche,Sophie Gil,Olivier Laprévote,Thierry Fournier,Séverine A Degrelle

PPAR research 2017:6139107 PubMed29225614

2017

New Transcriptional Reporters to Quantify and Monitor PPAR Activity.

Applications

Unspecified application

Species

Unspecified reactive species

Séverine A Degrelle,Hussein Shoaito,Thierry Fournier
View all publications

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