Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)
![Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)](https://www.abcam.co.jp/ps/products/146/ab146529/Images/ab146529-1-ab146529-Guanosine-539diphosphate-GDP-disodium-salt-Structure-CAS-7415692.jpg "Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)")
Key features and details
- Nucleoside diphosphate.
- CAS Number: 7415-69-2
- Purity: > 98%
Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate -
製品の詳細
Nucleoside diphosphate. -
別名
- GDP disodium salt
- GDP-Na3
- Guanosine 5'-diphosphate disodium salt
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生理活性の詳細
Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
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精製度
> 98% -
CAS 番号
7415-69-2 -
構造式
製品の特性
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分子量
487.17 -
分子式
C10H13N5Na2O11P2 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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由来
Synthetic
画像
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Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)2D chemical structure image of ab146529, Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (5)
ab146529 は 5 報の論文で使用されています。
- Rios L et al. Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nat Commun 14:4356 (2023). PubMed: 37468472
- Lattao R et al. Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins. Dev Cell N/A:N/A (2021). PubMed: 33725482
- Kutsch M et al. Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions. EMBO J 39:e104926 (2020). PubMed: 32510692
- Kovalski JR et al. The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Mol Cell 73:830-844.e12 (2019). PubMed: 30639242
- Kumar S et al. Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins. J Cell Biol 217:997-1013 (2018). PubMed: 29420192
