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AB146529

Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate

Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate

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(5 Publications)

MW 487.17 g/mol, Purity >98%. Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
1 Images
Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (AB146529)
  • Chemical Structure

Lab

Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (AB146529)

2D chemical structure image of ab146529, Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate

Key facts

CAS番号

7415-69-2

精製度

>98%

分子量

487.17 g/mol

分子式

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>3</sub>N<sub>5</sub>Na<sub>2</sub>O<sub>1</sub><sub>1</sub>P<sub>2</sub>

由来

Synthetic

溶解性

Soluble in water to 100 mM

生物学的記述

Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

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組合せ製品

Biochemicals

AB146528

Guanosine 5'-triphosphate [GTP] trisodium salt, signal transducing G proteins activator

Chemical Structure - Guanosine 5'-triphosphate [GTP] trisodium salt, signal transducing G proteins activator (AB146528)

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Reagents, Controls & Accessories

AB119211

InstantBlue® Coomassie Protein Stain (ISB1L)

Western blot - InstantBlue® Coomassie Protein Stain (ISB1L) (AB119211)

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Primary Antibodies

AB115777

Anti-beta Actin antibody [SP124] - Cytoskeleton Marker

20ul selling size|RabMAb|Lab Essentials|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Actin antibody [SP124] - Cytoskeleton Marker (AB115777)

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Primary Antibodies

AB108629

Anti-TUBA1B antibody [EPR1333] - Loading Control

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials

Flow Cytometry (Intracellular) - Anti-TUBA1B antibody [EPR1333] - Loading Control (AB108629)

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出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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製品プロトコール

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:4356 PubMed37468472

2023

Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Luis Rios,Suman Pokhrel,Sin-Jin Li,Gwangbeom Heo,Bereketeab Haileselassie,Daria Mochly-Rosen

Developmental cell 56:1000-1013.e6 PubMed33725482

2021

Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Ramona Lattao,Hélène Rangone,Salud Llamazares,David M Glover

The EMBO journal 39:e104926 PubMed32510692

2020

Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.

Applications

Unspecified application

Species

Unspecified reactive species

Miriam Kutsch,Linda Sistemich,Cammie F Lesser,Marcia B Goldberg,Christian Herrmann,Jörn Coers

Molecular cell 73:830-844.e12 PubMed30639242

2019

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

Applications

Unspecified application

Species

Unspecified reactive species

Joanna R Kovalski,Aparna Bhaduri,Ashley M Zehnder,Poornima H Neela,Yonglu Che,Glenn G Wozniak,Paul A Khavari

The Journal of cell biology 217:997-1013 PubMed29420192

2018

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Suresh Kumar,Ashish Jain,Farzin Farzam,Jingyue Jia,Yuexi Gu,Seong Won Choi,Michal H Mudd,Aurore Claude-Taupin,Michael J Wester,Keith A Lidke,Tor-Erik Rusten,Vojo Deretic
View all publications
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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
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