Gossypin, Chk1/Cdc25C activator

Key facts

CAS番号

652-78-8

精製度

>98%

製品の状態

Solid

form

作製由来

Hibiscus vitifolius

分子量

480.4 Da

分子式

C₂₁H₂₀O₁₃

PubChem

5281621

由来

Native

溶解性

Soluble in DMSO to 25 mM

化学名

Gossypin

生物学的記述

Chk1/Cdc25C activator. Antioxidant agent. Induces G2/M cell cycle arrest. Reduces lipid peroxidation. Shows antitumor, anti-ischemic and neuroprotective effects in vivo. Orally active.

Canonical smiles

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O

Isomeric smiles

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O

InChi

InChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1

InChiKey

SJRXVLUZMMDCNG-KKPQBLLMSA-N

IUPAC名

2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one