AB141699

ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist

Name: ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist (ab141699) | Abcam
Brand: Abcam Limited
SKU: AB141699
Price: 21000 JPY
Availability: InStock

Be the first to review this product! Submit a review

(3 Publications)

MW 283.41 Da, Purity >99%. Selective protease-activated receptor 2 (PAR2) antagonist (IC₅₀ = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.

1 Images

Chemical Structure - ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist (AB141699)

Chemical Structure

Lab

Chemical Structure - ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist (AB141699)

2D chemical structure image of ab141699, ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist

Key facts

CAS番号

789488-77-3

精製度

>99%

製品の状態

Solid

form

分子量

283.41 Da

分子式

C15H29N3O2

PubChem

9950925

由来

Synthetic

溶解性

Soluble in water to 100 mM

化学名

6-Amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one

生物学的記述

Selective protease-activated receptor 2 (PAR2) antagonist (IC₅₀ = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.

Canonical smiles

CC(C)CC(=O)N1CCN(CC1)C(=O)CCCCCN

InChi

InChI=1S/C15H29N3O2/c1-13(2)12-15(20)18-10-8-17(9-11-18)14(19)6-4-3-5-7-16/h13H,3-12,16H2,1-2H3

InChiKey

VRZYMMVEALDDBH-UHFFFAOYSA-N

IUPAC名

6-amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one

style

left-column

style

left-column

style

left-column

出荷温度及び保存条件

出荷温度

Ambient - Can Ship with Ice

短期保存温度

-20°C

長期保存温度

-20°C

保管に関する情報

Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Refer to SDS for further information.

style

left-column

style

left-column

style

left-column

製品プロトコール

Visit the General protocols
Visit the Troubleshooting

style

left-column

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Clinical and translational medicine 15:e70291 PubMed40147022

2025

The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing.

Applications

Unspecified application

Species

Unspecified reactive species

Na Zhao,Guojian Wang,Shuang Long,Xiaofan Lv,Xinze Ran,Junping Wang,Yongping Su,Tao Wang

American journal of cancer research 9:1995-2006 PubMed31598400

2019

Protease activated receptor 2 mediates tryptase-induced cell migration through MYO10 in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoli Zhang,Qing Fang,Yiming Ma,Shuangmei Zou,Qian Liu,Hongying Wang

Pain 155:1328-38 PubMed24726923

2014

Tryptase-PAR2 axis in experimental autoimmune prostatitis, a model for chronic pelvic pain syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Kenny Roman,Joseph D Done,Anthony J Schaeffer,Stephen F Murphy,Praveen Thumbikat

View all publications

style

left-column

style

left-column

style

right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist