Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent (ab145212)

Abundant essential n-3 polyunsaturated fatty acid in the CNS, shown to play a major anti-inflammatory role. Prevents LPS-induced dendritic cell maturation, characterized by a lack of proinflammatory cytokine production. Improves the nitroso-redox balance and reduces VEGF-mediated angiogenic signaling in microvascular endothelial cells. Inhibits Aβ1-42 fibrillation and toxicity in vitro. Retinoid X receptor (RXR) ligand.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Synthetic