Daptomycin, Lipopeptide antibiotic (ab141204)
Key features and details
- Lipopeptide antibiotic
- CAS Number: 103060-53-3
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Steptomyces nouseri
製品の概要
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製品名
Daptomycin, Lipopeptide antibiotic -
製品の詳細
Lipopeptide antibiotic -
別名
- LY146032
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生理活性の詳細
Lipopeptide antibiotic. Gram-positive bacterial membrane integrity antagonist. Does not interact with p450 cytochromes. Concentration-dependent antibacterial activity in vitro and in vivo.
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CAS 番号
103060-53-3 -
構造式
製品の特性
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体系名
(αS)-N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxobenzenebutanoic acid (13-4) lactone -
分子量
1620.69 -
分子式
C72H101N17O26 -
PubChem 登録番号
16129629 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
NC(=O)C[C@H](NC(=O)[C@H](Cc1cnc2ccccc12)NC(=O)CCCCCCCCC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]4C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@@H]([C@H](C)CC(=O)O)C(=O)N[C@@H](CC(=O)c3ccccc3N)C(=O)O[C@@H]4C -
由来
Steptomyces nouseri
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研究分野
画像
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Chemical Structure - Daptomycin, Lipopeptide antibiotic (ab141204)2D chemical structure image of ab141204, Daptomycin, Lipopeptide antibiotic
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab141204 は 1 報の論文で使用されています。
- Guyet A et al. Insights into the Roles of Lipoteichoic Acids and MprF in Bacillus subtilis. mBio 14:e0266722 (2023). PubMed: 36744964