Cycloheximide, Protein synthesis inhibitor (ab120093)
Key features and details
- Protein synthesis inhibitor
- CAS Number: 66-81-9
- Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Cycloheximide, Protein synthesis inhibitor -
製品の詳細
Protein synthesis inhibitor -
生理活性の詳細
Protein synthesis inhibitor. Antifungal antibiotic.
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CAS 番号
66-81-9 -
構造式
製品の特性
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体系名
3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide -
分子量
281.35 -
分子式
C15H23NO4 -
PubChem 登録番号
6197 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 25 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=C2CC(C[C@@H](O)[C@@H]1C[C@@H](C)C[C@H](C)C1=O)CC(=O)N2 -
由来
Synthetic
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研究分野
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab120093の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Functional Studies |
Use at an assay dependent concentration.
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| 特記事項 |
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Functional Studies
Use at an assay dependent concentration. |
画像
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Chemical Structure - Cycloheximide, Protein synthesis inhibitor (ab120093)2D chemical structure image of ab120093, Cycloheximide, Protein synthesis inhibitor
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Functional Studies - Cycloheximide, Protein synthesis inhibitor (ab120093)Functional assays: Caspase 8 (active) FITC Staining Kit (ab65614)
Active caspase 8 in control Jurkat cells (10e6/mL) or cells treated for five hours with 10 ug/mL Cyclohexamide (CHX) (ab120093) or four hours with 25 ug/mL Mitomycin C (MitoC) (ab120797). Background signal subtracted, duplicates; +/- SD.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (29)
ab120093 は 29 報の論文で使用されています。
- Wu T et al. KARR-seq reveals cellular higher-order RNA structures and RNA-RNA interactions. Nat Biotechnol N/A:N/A (2024). PubMed: 38238480
- Zhou Y et al. Nudt21-mediated alternative polyadenylation of MZT1 3'UTR contributes to pancreatic cancer progression. iScience 27:108822 (2024). PubMed: 38303721
- Solomon SL & Bryson BD Single-cell analysis reveals a weak macrophage subpopulation response to Mycobacterium tuberculosis infection. Cell Rep 42:113418 (2023). PubMed: 37963018
- Zhang B et al. The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy. Autophagy 19:1916-1933 (2023). PubMed: 36588386
- Wu X et al. Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS. Acta Pharm Sin B 13:113-127 (2023). PubMed: 36815040