Clozapine N-oxide, Metabolite of Clozapine (ab141704)
Key features and details
- Metabolite of Clozapine
- CAS Number: 34233-69-7
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Clozapine N-oxide, Metabolite of Clozapine -
製品の詳細
Metabolite of Clozapine -
生理活性の詳細
Metabolite of atypical antipsychotic Clozapine (ab120019). Active in vitro and in vivo.
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精製度
> 99% -
CAS 番号
34233-69-7 -
構造式
製品の特性
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体系名
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e](1,4)diazepine N-oxide -
分子量
342.83 -
分子式
C18H19ClN4O -
PubChem 登録番号
36727 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2O)C=C(C=C4)Cl -
由来
Synthetic
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研究分野
関連製品
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Alternative Versions
画像
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Chemical Structure - Clozapine N-oxide, Metabolite of Clozapine (ab141704)2D chemical structure image of ab141704, Clozapine N-oxide, Metabolite of Clozapine
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (24)
ab141704 は 24 報の論文で使用されています。
- Chen L et al. Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits. Signal Transduct Target Ther 8:225 (2023). PubMed: 37280192
- Gu X et al. Neurons in the caudal ventrolateral medulla mediate descending pain control. Nat Neurosci 26:594-605 (2023). PubMed: 36894654
- Chen W et al. Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation. Cell Metab 35:786-806.e13 (2023). PubMed: 37075752
- Tan N et al. Lateral Hypothalamus Calcium/Calmodulin-Dependent Protein Kinase II α Neurons Encode Novelty-Seeking Signals to Promote Predatory Eating. Research (Wash D C) 2022:9802382 (2022). PubMed: 36061821
- Zhao J et al. Activated astrocytes attenuate neocortical seizures in rodent models through driving Na+-K+-ATPase. Nat Commun 13:7136 (2022). PubMed: 36414629