Cisplatin, antineoplastic agent (ab141398)
Key features and details
- Potent, broad spectrum antineoplastic agent
- CAS Number: 15663-27-1
- Soluble in water to 5 mM (with sonication) and in 0.9% w/w NaCl to 5 mM (with sonication)
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Cisplatin, antineoplastic agent -
製品の詳細
Potent, broad spectrum antineoplastic agent -
CAS 番号
15663-27-1 -
構造式
製品の特性
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体系名
(SP-4-2)-Diamminedichloroplatinum -
分子量
300.05 -
分子式
Cl2H6N2Pt -
PubChem 登録番号
441203 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 5 mM (with sonication) and in 0.9% w/w NaCl to 5 mM (with sonication) -
使用に関する注意
Unstable; make up solutions fresh and use immediately.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
N.N.Cl[Pt+2]Cl -
由来
Synthetic
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研究分野
画像
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Chemical Structure - Cisplatin, antineoplastic agent (ab141398)2D chemical structure image of ab141398, Cisplatin, antineoplastic agent
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (9)
ab141398 は 9 報の論文で使用されています。
- Qian T et al. β-elemene enhances cisplatin sensitivity of non-small cell lung cancer cells via the miR-17-5p/STAT3 axis. Chem Biol Drug Des 103:e14395 (2024). PubMed: 37973414
- Yan L et al. Loss of SETD2-mediated downregulation of intracellular and exosomal miRNA-10b determines MAPK pathway activation and multidrug resistance in renal cancer. Mol Carcinog 62:1770-1781 (2023). PubMed: 37589422
- Tröndle K et al. Deep Learning-Assisted Nephrotoxicity Testing with Bioprinted Renal Spheroids. Int J Bioprint 8:528 (2022). PubMed: 35702333
- Mahmood N et al. S-adenosylmethionine in combination with decitabine shows enhanced anti-cancer effects in repressing breast cancer growth and metastasis. J Cell Mol Med 24:10322-10337 (2020). PubMed: 32720467
- Luo R et al. Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment. Clin Cancer Res 25:7243-7255 (2019). PubMed: 31506388
- Tan Z et al. Environmental stresses induce karyotypic instability in colorectal cancer cells. Mol Biol Cell 30:42-55 (2019). PubMed: 30379607
- Carter RJ et al. Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death Dis 10:912 (2019). PubMed: 31801952
- Qin W et al. Inhibiting microRNA-449 Attenuates Cisplatin-Induced Injury in NRK-52E Cells Possibly via Regulating the SIRT1/P53/BAX Pathway. Med Sci Monit 22:818-23 (2016). PubMed: 26968221
- Black JC et al. Regulation of Transient Site-specific Copy Gain by MicroRNA. J Biol Chem 291:4862-71 (2016). PubMed: 26755726