CHM1, Antitumor agent (ab141225)
Key features and details
- Potent antitumor agent
- CAS Number: 154554-41-3
- Purity: > 99%
- Soluble in DMSO to 5 mM (with warming) and in ethanol to 5 mM (with warming)
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
CHM1, Antitumor agent -
製品の詳細
Potent antitumor agent -
生理活性の詳細
Potent antitumor agent. Antiproliferative, anti-angiogenic and anti-apoptotic in a dose dependent manner. Reduces cell viability (IC50 = 0.13 - 8.2 μM) and tumor invasion. Active in vitro and in vivo. Increases expression of DR5, TRIAL, p53. Reduces tumor polymerisation and caspase activation.
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精製度
> 99% -
CAS 番号
154554-41-3 -
構造式
製品の特性
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体系名
6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one -
分子量
283.26 -
分子式
C16H10FNO3 -
PubChem 登録番号
375860 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 5 mM (with warming) and in ethanol to 5 mM (with warming) -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
Fc4ccccc4C=2Nc1cc3OCOc3cc1C(=O)C=2 -
由来
Synthetic
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研究分野
画像
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Chemical Structure - CHM1, Antitumor agent (ab141225)2D chemical structure image of ab141225, CHM1, Antitumor agent
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab141225 は論文での使用が確認できていません。
