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AB120167

CGP 35348, GABAB antagonist

CGP 35348, GABAB antagonist

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(2 Publications)

MW 225.22 Da. Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.

別名を表示する

BcDNA:GH07312, CG6706, CT20836, D Gaba2, FLJ36928, FLJ92613, G-protein coupled receptor 51, GAB B R2, GABA-B receptor 1, GABA-B receptor 2, GABA-B-R1, GABA-B-R2, GABAB subunit 1c, GABBR1, GABBR1 3, GABR1_HUMAN, GABR2_HUMAN, GH07312, GPR 51, GPRC 3B, GPRC3A, Gamma aminobutyric acid (GABA) B receptor 1, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA B receptor 2, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, Gb 2, Gb1, HG 20, HRIHFB2099, Metabotropic GABA B receptor subtype 2, OTTHUMP00000021776, OTTHUMP00000063797, R2 SUBUNIT, Seven transmembrane helix receptor, dJ271M21.1.1, dJ271M21.1.2

1 Images
Chemical Structure - CGP 35348, GABAB antagonist (AB120167)
  • Chemical Structure

Lab

Chemical Structure - CGP 35348, GABAB antagonist (AB120167)

2D chemical structure image of ab120167, CGP 35348, GABAB antagonist

Key facts

CAS番号

123690-79-9

製品の状態

Solid

form

分子量

225.22 Da

分子式

C<sub>8</sub>H<sub>2</sub><sub>0</sub>NO<sub>4</sub>P

PubChem

107699

由来

Synthetic

溶解性

Soluble in water to 100 mM

化学名

3-Aminopropyl(diethoxymethyl)phosphinic acid

生物学的記述

Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.

Canonical smiles

CCOC(OCC)P(=O)(CCCN)O

InChi

InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)

InChiKey

QIIVUOWTHWIXFO-UHFFFAOYSA-N

IUPAC名

3-aminopropyl(diethoxymethyl)phosphinic acid

出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store under desiccating conditions|The product can be stored for up to 12 months

製品プロトコール

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Reproductive medicine and biology 22:e12528 PubMed37476368

2023

Gamma-aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABA and GABA receptors.

Applications

Unspecified application

Species

Unspecified reactive species

Veronika Kovaříková,Alexandra Špirková,Zuzana Šefčíková,Jozef Pisko,Laura Kalatová,Juraj Koppel,Dušan Fabian,Štefan Čikoš

Psychopharmacology 217:167-76 PubMed21484240

2011

GABA(B) receptor blockade in the hippocampus affects sensory and sensorimotor gating in Long-Evans rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jingyi Ma,L Stan Leung
View all publications

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