AB141420

Calcein AM, fluorescent dye for cell viability

Name: Calcein AM, fluorescent dye for cell viability (ab141420) | Abcam
Brand: Abcam Limited
SKU: AB141420
Rating: 5 (1 reviews)

(1 Review)

(23 Publications)

MW 994.9 Da, Purity >96%. Cell permeant probe used to determine cell viability in most eukaryotic cells. In live cells the nonfluorescent calcein AM is converted to a green-fluorescent calcein after acetoxymethyl ester hydrolysis by intracellular esterases.

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Chemical Structure - Calcein AM, fluorescent dye for cell viability (AB141420)

Chemical Structure

Lab

Chemical Structure - Calcein AM, fluorescent dye for cell viability (AB141420)

2D chemical structure image of ab141420, Calcein AM, fluorescent dye for cell viability

Key facts

CAS番号

148504-34-1

精製度

>96%

製品の状態

Solid

form

分子量

994.9 Da

分子式

C46H46N2O23

PubChem

390986

由来

Synthetic

溶解性

Soluble in DMSO

化学名

Calcein AM

生物学的記述

Cell permeant probe used to determine cell viability in most eukaryotic cells. In live cells the nonfluorescent calcein AM is converted to a green-fluorescent calcein after acetoxymethyl ester hydrolysis by intracellular esterases.

Canonical smiles

CC(=O)OCOC(=O)CN(CC1=CC2=C(C=C1OC(=O)C)OC3=C(C24C5=CC=CC=C5C(=O)O4)C=C(C(=C3)OC(=O)C)CN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

InChi

InChI=1S/C46H46N2O23/c1-25(49)60-21-64-41(55)17-47(18-42(56)65-22-61-26(2)50)15-31-11-35-39(13-37(31)68-29(5)53)70-40-14-38(69-30(6)54)32(12-36(40)46(35)34-10-8-7-9-33(34)45(59)71-46)16-48(19-43(57)66-23-62-27(3)51)20-44(58)67-24-63-28(4)52/h7-14H,15-24H2,1-6H3

InChiKey

BQRGNLJZBFXNCZ-UHFFFAOYSA-N

IUPAC名

acetyloxymethyl 2-[[2-(acetyloxymethoxy)-2-oxoethyl]-[[3',6'-diacetyloxy-7'-[[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]methyl]-3-oxospiro[2-benzofuran-1,9'-xanthene]-2'-yl]methyl]amino]acetate

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出荷温度及び保存条件

出荷温度

Ambient - Can Ship with Ice

短期保存温度

-20°C

長期保存温度

-20°C

保管に関する情報

It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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文献 (23)

Recent publications for all applications. Explore the full list and refine your search

Gels (Basel, Switzerland) 10: PubMed39590101

2024

In Vitro Investigation of 3D Printed Hydrogel Scaffolds with Electrospun Tidemark Component for Modeling Osteochondral Interface.

Applications

Unspecified application

Species

Unspecified reactive species

Victoria Effiong Effanga,Dana Akilbekova,Fariza Mukasheva,Xiao Zhao,Dilhan M Kalyon,Cevat Erisken

EMBO molecular medicine 16:1755-1790 PubMed39030302

2024

LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Wang,Qiyao Chai,Zehui Lei,Yiru Wang,Jiehua He,Pupu Ge,Zhe Lu,Lihua Qiang,Dongdong Zhao,Shanshan Yu,Changgen Qiu,Yanzhao Zhong,Bing-Xi Li,Lingqiang Zhang,Yu Pang,George Fu Gao,Cui Hua Liu

Gels (Basel, Switzerland) 10: PubMed38920952

2024

Impact of Hydroxyapatite on Gelatin/Oxidized Alginate 3D-Printed Cryogel Scaffolds.

Applications

Unspecified application

Species

Unspecified reactive species

Ainur Zhanbassynova,Fariza Mukasheva,Madi Abilev,Dmitriy Berillo,Alexander Trifonov,Dana Akilbekova

ACS omega 9:24095-24104 PubMed38854553

2024

Hydrogel-Based Oxygen and Drug Delivery Dressing for Improved Wound Healing.

Applications

Unspecified application

Species

Unspecified reactive species

Wen Ren,Mia Sands,Xiaoxue Han,Michael Tsipursky,Joseph Irudayaraj

Nature communications 15:3435 PubMed38653959

2024

Exosome-coated oxygen nanobubble-laden hydrogel augments intracellular delivery of exosomes for enhanced wound healing.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoxue Han,Chaimongkol Saengow,Leah Ju,Wen Ren,Randy H Ewoldt,Joseph Irudayaraj

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11:e2308701 PubMed38460168

2024

Framework Nucleic Acids-Based VEGF Signaling Activating System for Angiogenesis: A Dual Stimulation Strategy.

Applications

Unspecified application

Species

Unspecified reactive species

Yichen Ge,Qingxuan Wang,Yangxue Yao,Qin Xin,Jiafei Sun,Wen Chen,Yunfeng Lin,Xiaoxiao Cai

Cellular and molecular biology (Noisy-le-Grand, France) 69:227-232 PubMed37953558

2023

GSDMD inhibitor protects chondrocyte from mechanical injury in human articular cartilage.

Applications

Unspecified application

Species

Unspecified reactive species

Chunye Tan,Linwei Li,Wenming Ma,Jinlong Zhang,Weiqi Ling

Genomics, proteomics & bioinformatics 21:1246-1259 PubMed37121272

2023

The Proteome Landscape of Human Placentas for Monochorionic Twins with Selective Intrauterine Growth Restriction.

Applications

Unspecified application

Species

Unspecified reactive species

Xin-Lu Meng,Peng-Bo Yuan,Xue-Ju Wang,Jing Hang,Xiao-Ming Shi,Yang-Yu Zhao,Yuan Wei

Biomedicines 11: PubMed37189610

2023

Dimethyloxalylglycine Attenuates Steroid-Associated Endothelial Progenitor Cell Impairment and Osteonecrosis of the Femoral Head by Regulating the HIF-1α Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Wenkai Shao,Zilin Li,Bo Wang,Song Gong,Ping Wang,Beite Song,Zhixiang Chen,Yong Feng

Journal of animal science and biotechnology 14:29 PubMed36922863

2023

Ferroptosis is involved in deoxynivalenol-induced intestinal damage in pigs.

Applications

Unspecified application

Species

Unspecified reactive species

Meng Liu,Lei Zhang,Yixin Mo,Jiahuan Li,Jiacheng Yang,Juan Wang,Niel Alexander Karrow,Hao Wu,Lvhui Sun

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

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Calcein AM, fluorescent dye for cell viability