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AB141323

BD 1063 dihydrochloride, sigma-1 antagonist

BD 1063 dihydrochloride, sigma-1 antagonist

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(1 Publication)

MW 346.1 Da, Purity >99%. Potent selective σ1 receptor antagonist (Ki values are 9 and 449 nM at σ1 and σ2 receptors, respectively). Shown to prevent hyperlocomotion, active in vivo.
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Chemical Structure - BD 1063 dihydrochloride, sigma-1 antagonist (AB141323)
  • Chemical Structure

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Chemical Structure - BD 1063 dihydrochloride, sigma-1 antagonist (AB141323)

2D chemical structure image of ab141323, BD 1063 dihydrochloride, sigma-1 antagonist

Key facts

CAS番号

150208-28-9

精製度

>99%

製品の状態

Solid

form

分子量

346.1 Da

分子式

C<sub>1</sub><sub>3</sub>H<sub>2</sub><sub>0</sub>Cl<sub>4</sub>N<sub>2</sub>

PubChem

11617161

由来

Synthetic

溶解性

Soluble in water to 100 mM

化学名

BD 1063 Dihydrochloride

生物学的記述

Potent selective σ1 receptor antagonist (Ki values are 9 and 449 nM at σ1 and σ2 receptors, respectively). Shown to prevent hyperlocomotion, active in vivo.

Canonical smiles

CN1CCN(CC1)CCC2=CC(=C(C=C2)Cl)Cl.Cl.Cl

InChi

InChI=1S/C13H18Cl2N2.2ClH/c1-16-6-8-17(9-7-16)5-4-11-2-3-12(14)13(15)10-11;;/h2-3,10H,4-9H2,1H3;2*1H

InChiKey

NXFDBTLQOARIMH-UHFFFAOYSA-N

IUPAC名

1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine;dihydrochloride

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組合せ製品

Biochemicals

AB120234

PD 98059, MEK1 inhibitor

Immunocytochemistry/ Immunofluorescence - PD 98059, MEK1 inhibitor (AB120234)

  • 0
  • 0
Primary Antibodies

AB246518

Anti-CXCL13 antibody [EPR23400-92]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCL13 antibody [EPR23400-92] (AB246518)

  • 5
  • 1
Primary Antibodies

AB105227

Anti-ICOS antibody [SP98]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICOS antibody [SP98] (AB105227)

  • 3
  • 2
Primary Antibodies

AB306503

PE Anti-CD10 antibody [SP179] (N-terminal)

RabMAb|Recombinant

  • 0
  • 0
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出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
Ambient
長期保存温度
Ambient
保管に関する情報
The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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製品プロトコール

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cell calcium 58:196-207 PubMed26077147

2015

Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Jeffrey L Barr,Elena Deliu,G Cristina Brailoiu,Pingwei Zhao,Guang Yan,Mary E Abood,Ellen M Unterwald,Eugen Brailoiu
View all publications
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