AB144924

BAPTA, extracellular calcium chelator

Name: BAPTA, extracellular calcium chelator (ab144924) | Abcam
Brand: Abcam Limited
SKU: AB144924
Price: 22000 JPY
Availability: InStock

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(2 Publications)

MW 476.4 Da. Selective, membrane impermeable extracellular calcium chelator. Binds Ca²⁺ ions in a 2:1 ratio. Shows 105-fold greater affinity for Ca²⁺ than Mg²⁺. BAPTA-AM (ab120503) and BAPTA sodium salt (ab120449) analog.

Key facts

CAS番号

85233-19-8

製品の状態

Powder

form

分子量

476.4 Da

分子式

C22H24N2O10

PubChem

104751

由来

Synthetic

溶解性

Soluble in DMSO to 25 mM

化学名

Bapta

生物学的記述

Selective, membrane impermeable extracellular calcium chelator. Binds Ca²⁺ ions in a 2:1 ratio. Shows 105-fold greater affinity for Ca²⁺ than Mg²⁺. BAPTA-AM (ab120503) and BAPTA sodium salt (ab120449) analog.

Canonical smiles

C1=CC=C(C(=C1)N(CC(=O)O)CC(=O)O)OCCOC2=CC=CC=C2N(CC(=O)O)CC(=O)O

InChi

InChI=1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)

InChiKey

FTEDXVNDVHYDQW-UHFFFAOYSA-N

IUPAC名

2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid

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出荷温度及び保存条件

出荷温度

Ambient - Can Ship with Ice

短期保存温度

-20°C

長期保存温度

-20°C

保管に関する情報

Store under desiccating conditions|The product can be stored for up to 12 months

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 295:10138-10152 PubMed32385113

2020

Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies.

Applications

Unspecified application

Species

Unspecified reactive species

Janin Lautenschläger,Sara Wagner-Valladolid,Amberley D Stephens,Ana Fernández-Villegas,Colin Hockings,Ajay Mishra,James D Manton,Marcus J Fantham,Meng Lu,Eric J Rees,Clemens F Kaminski,Gabriele S Kaminski Schierle

Autophagy 13:2086-2103 PubMed28933598

2017

Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Qiang,Ashley Sample,Christopher R Shea,Keyoumars Soltani,Kay F Macleod,Yu-Ying He

View all publications

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Abcam product promise

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BAPTA, extracellular calcium chelator