Antimycin A (DMSO Solution) (ab147494)
Key features and details
- Antibiotic; induces apoptosis
- CAS Number: 1397-94-0
- Supplied in DMSO (100 mM)
- Form / State: Liquid
- Source: Synthetic
製品の概要
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製品名
Antimycin A (DMSO Solution) -
製品の詳細
Antibiotic; induces apoptosis -
生理活性の詳細
Antibiotic. Induces apoptosis and inhibits mitochondrial electron transport specifically between cytochromes b and c1.
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CAS 番号
1397-94-0 -
構造式
製品の特性
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体系名
[(2R,3S,6S,7R,8R)-3-[(3-Formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate (for Antimycin A1: R = C6H13) -
分子量
548.63 -
分子式
C28H40N2O9 (for Antimycin A1, R = C6H13) -
PubChem 登録番号
14957 -
保存方法
Shipped at Room Temperature. Store at -20°C long term. -
溶解性
Supplied in DMSO (100 mM) -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab147494 は 3 報の論文で使用されています。
- Ge Y et al. Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury. Mol Ther Nucleic Acids 19:1250-1265 (2020). PubMed: 32074940
- Yu HF et al. HB-EGF Ameliorates Oxidative Stress-Mediated Uterine Decidualization Damage. Oxid Med Cell Longev 2019:6170936 (2019). PubMed: 31885807
- Arnandis T et al. Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion. Dev Cell 47:409-424.e9 (2018). PubMed: 30458137