AMI 1, protein arginine methyltransferase inhibitor (ab141472)
Key features and details
- Potent, selective and reversible protein arginine methyltransferase inhibitor
- CAS Number: 20324-87-2
- Purity: = 99%
Insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL in H2O
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
AMI 1, protein arginine methyltransferase inhibitor -
製品の詳細
Potent, selective and reversible protein arginine methyltransferase inhibitor -
生理活性の詳細
Potent, selective and reversible protein arginine methyltransferase inhibitor (IC50 = 1.63 μM). ROS° scavenger with antioxidant effects (IC50 = 8.3 μM). Inhibits arginine in vitro without competing for the AdoMet binding site. Modulates nuclear receptor-regulated transcription in vivo. Cell-permeable.
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精製度
= 99% -
CAS 番号
20324-87-2 -
構造式
製品の特性
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体系名
7,7'-(Carbonyldiimino)bis[4-hydroxy2-naphthalenesulfonic acid] disodium salt
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分子量
548.45 -
分子式
C21H14N2Na2O9S2 -
PubChem 登録番号
88489 -
保存方法
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
溶解性
Insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL in H2O
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+] -
由来
Synthetic
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研究分野
画像
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Chemical Structure - AMI 1, protein arginine methyltransferase inhibitor (ab141472)2D chemical structure image of ab141472, AMI 1, protein arginine methyltransferase inhibitor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab141472 は論文での使用が確認できていません。
