AG 1296, protein tyrosine kinase inhibitor (ab141170)
Key features and details
- Potent specific PDGF receptor tyrosine kinase inhibitor
- CAS Number: 146535-11-7
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
AG 1296, protein tyrosine kinase inhibitor -
製品の詳細
Potent specific PDGF receptor tyrosine kinase inhibitor -
精製度
> 99% -
CAS 番号
146535-11-7 -
構造式
製品の特性
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体系名
6,7-Dimethoxy-2-phenylquinoxaline -
分子量
266.30 -
分子式
C16H14N2O2 -
PubChem 登録番号
2049 -
保存方法
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 10 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
COc1cc2nc(cnc2cc1OC)c3ccccc3 -
由来
Synthetic
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研究分野
画像
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Chemical Structure - AG 1296, protein tyrosine kinase inhibitor (ab141170)2D chemical structure image of ab141170, AG 1296, protein tyrosine kinase inhibitor
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (4)
ab141170 は 4 報の論文で使用されています。
- Tsai YC et al. PDGF-AA activates AKT and ERK signaling for testicular interstitial Leydig cell growth via primary cilia. J Cell Biochem 124:89-102 (2023). PubMed: 36306470
- Teske NC et al. Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood-brain barrier function. J Neuroinflammation 20:267 (2023). PubMed: 37978545
- Contreras O et al. Cross-talk between TGF-ß and PDGFRa signaling pathways regulates the fate of stromal fibro-adipogenic progenitors. J Cell Sci 132:N/A (2019). PubMed: 31434718
- Wu Q et al. miR-1224-5p Mediates Mitochondrial Damage to Affect Silica-Induced Pulmonary Fibrosis by Targeting BECN1. Int J Mol Sci 18:N/A (2017). PubMed: 29112159
