AB142090

ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor

Name: ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor (ab142090) | Abcam
Brand: Abcam Limited
SKU: AB142090
Price: 40000 JPY
Availability: InStock

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(1 Publication)

MW 403.52 g/mol, Purity >98%. Potent, selective ACC2 (Acetyl-CoA Carboxylase) inhibitor (IC₅₀ values are 28 and 210 nM for hACC2 and hACC1 respectively). Active in vivo and in vitro.

1 Images

Chemical Structure - ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor (AB142090)

Chemical Structure

Lab

Chemical Structure - ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor (AB142090)

2D chemical structure image of ab142090, ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor

Key facts

精製度

>98%

製品の状態

Solid

form

分子量

403.52 g/mol

分子式

C19H21N3O3S2

由来

Synthetic

溶解性

Soluble in DMSO

生物学的記述

Potent, selective ACC2 (Acetyl-CoA Carboxylase) inhibitor (IC₅₀ values are 28 and 210 nM for hACC2 and hACC1 respectively). Active in vivo and in vitro.

Canonical smiles

CC(=O)NC(C)C1CNC(S1)C3CNC(OC2CCC(OC(C)C)CC2)S3

InChi

InChI=1S/C19H21N3O3S2c1-11(2)24-14-5-7-15(8-6-14)25-19-21-10-17(27-19)18-20-9-16(26-18)12(3)22-13(4)23/h5-12H,1-4H3,(H,22,23)

InChiKey

CVAJIWQTUPPAIF-UHFFFAOYSA-N

IUPAC名

N-(1-(2'-(4-Isopropoxyphenoxy)-2,5'-bithiazol-5-yl)ethyl)acetamide

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製品の詳細

This product is manufactured by BioVision, an Abcam company and was previously called 1717 ACC2 Inhibitor. 1717-1 is the same size as the 1 mg size of ab142090.

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出荷温度及び保存条件

出荷温度

Ambient - Can Ship with Ice

短期保存温度

-20°C

長期保存温度

-20°C

保管に関する情報

Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of clinical investigation 131: PubMed34255743

2021

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.

Applications

Unspecified application

Species

Unspecified reactive species

Julius Brandenburg,Sebastian Marwitz,Simone C Tazoll,Franziska Waldow,Barbara Kalsdorf,Tim Vierbuchen,Thomas Scholzen,Annette Gross,Svenja Goldenbaum,Alexandra Hölscher,Martina Hein,Lara Linnemann,Maja Reimann,Andreas Kispert,Michael Leitges,Jan Rupp,Christoph Lange,Stefan Niemann,Jochen Behrends,Torsten Goldmann,Holger Heine,Ulrich E Schaible,Christoph Hölscher,Dominik Schwudke,Norbert Reiling

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor