8-Br-cAMP (8-Bromo-cAMP), PKA activator (ab141448)
Key features and details
- cAMP analog. PKA activator.
- CAS Number: 76939-46-3
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
8-Br-cAMP (8-Bromo-cAMP), PKA activator -
製品の詳細
cAMP analog. PKA activator. -
別名
- 8-Bromo-cAMP
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精製度
> 98% -
CAS 番号
76939-46-3 -
構造式
製品の特性
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体系名
8-Bromoadenosine-3′,5′-cyclic monophosphate sodium salt -
分子量
430.09 -
分子式
C10H10BrN5NaO6P -
PubChem 登録番号
23712387 -
保存方法
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+] -
由来
Synthetic
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研究分野
画像
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Chemical Structure - 8-Br-cAMP (8-Bromo-cAMP), PKA activator (ab141448)2D chemical structure image of ab141448, 8-Br-cAMP (8-Bromo-cAMP), PKA activator
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (6)
ab141448 は 6 報の論文で使用されています。
- Han M et al. Increased expression of HMGB1 in the implantation phase endometrium is related to recurrent implantation failure. Mol Biol Rep 49:1701-1710 (2022). PubMed: 35031923
- Chen Y et al. Diuretic Action of Apelin-13 Mediated by Inhibiting cAMP/PKA/sPRR Pathway. Front Physiol 12:642274 (2021). PubMed: 33868005
- Zhou M et al. Decreased PIBF1/IL6/p-STAT3 during the mid-secretory phase inhibits human endometrial stromal cell proliferation and decidualization. J Adv Res 30:15-25 (2021). PubMed: 34026283
- Zhou X et al. Loss of CDYL Results in Suppression of CTNNB1 and Decreased Endometrial Receptivity. Front Cell Dev Biol 8:105 (2020). PubMed: 32158757
- Tishchenko A et al. Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells. Cancers (Basel) 12:N/A (2020). PubMed: 33003486
- Zhou M et al. miR-196a overexpression activates the MEK/ERK signal and represses the progesterone receptor and decidualization in eutopic endometrium from women with endometriosis. Hum Reprod N/A:N/A (2016). PubMed: 27619769
