5-Ethynyluridine (5-EU), Uridine analog (ab146642)
Key features and details
- Uridine analog. Click chemistry RNA transcription label.
- CAS Number: 69075-42-9
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
5-Ethynyluridine (5-EU), Uridine analog -
製品の詳細
Uridine analog. Click chemistry RNA transcription label. -
別名
- 5-EU
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生理活性の詳細
Uridine (ab143255) analog. Click chemistry RNA transcription label. Incorporates into RNA during active RNA synthesis. Does not incorporate into DNA. Reacts with azide-containing detection reagents. -
精製度
> 99% -
CAS 番号
69075-42-9 -
構造式
製品の特性
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体系名
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynylpyrimidine-2,4-dione -
分子量
268.22 -
分子式
C11H12N2O6 -
PubChem 登録番号
14885960 -
保存方法
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C#CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O -
由来
Synthetic
画像
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Chemical Structure - 5-Ethynyluridine (5-EU), Uridine analog (ab146642)2D chemical structure image of ab146642, 5-Ethynyluridine (5-EU), Uridine analog
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (4)
ab146642 は 4 報の論文で使用されています。
- Zhang J et al. Deciphering a global source of non-genetic heterogeneity in cancer cells. Nucleic Acids Res 51:9019-9038 (2023). PubMed: 37587722
- Perea-Resa C et al. Cohesin Removal Reprograms Gene Expression upon Mitotic Entry. Mol Cell 78:127-140.e7 (2020). PubMed: 32035037
- Pavlova NN et al. Translation in amino-acid-poor environments is limited by tRNAGln charging. Elife 9:N/A (2020). PubMed: 33289483
- Prusty AB et al. Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation. J Cell Biol 216:2391-2407 (2017). PubMed: 28637748
