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24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite (ab141633)

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Chemical Structure - 24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite (ab141633)

    Key features and details

    • Endogenous cholesterol metabolite
    • CAS Number: 77058-74-3
    • Purity: > 95%
    • Soluble in ethanol to 25 mM
    • Form / State: Solid
    • Source: Synthetic

    製品の概要

    • 製品名

      24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite

    • 製品の詳細

      Endogenous cholesterol metabolite

    • 生理活性の詳細

      Endogenous cholesterol metabolite. Suppresses SREBP activation in the regulation of hepatic cholesterol metabolism in vivo.

    • 精製度

      > 95%

    • 特記事項

      We recommend immediate use of this product following dissolution.

      Although reported to be soluble in DMSO our analysis shows gentle heating is required to achieve this, leading to significant decomposition. The product is soluble in ethanol, however we found extended time or gentle warming once again led to some degree of decomposition.

    • CAS 番号

      77058-74-3

    • 構造式

      Chemical Structure

    製品の特性

    画像

    • Chemical Structure - 24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite (ab141633)
      Chemical Structure - 24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite (ab141633)
      2D chemical structure image of ab141633, 24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (1)

    ab141633 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab141633 は 1 報の論文で使用されています。

    • Saito H  et al. Hydroxylation site-specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR. J Biol Chem 299:102733 (2023). PubMed: 36423680

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